A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

NCT ID: NCT06025578

This clinical trial is studying a new medication called BMS-986278 to see how well it works, how safe it is, and how well patients tolerate it for people with a condition called Progressive Pulmona...

Recruiting

Phase: PHASE3 Conditions: Progressive Pulmonary Fibrosis

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

NCT ID: NCT05296798

This clinical trial, called the heredERA Breast Cancer study, is looking at the effectiveness and safety of a new medication called giredestrant when combined with Phesgo (which includes pertuzumab...

Recruiting

Phase: PHASE3 Conditions: Locally Advanced or Metastatic Breast Cancer

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

NCT ID: NCT05911295

This clinical trial is studying two different treatment options for patients with urothelial cancer, which can affect the bladder, kidneys, or urinary tubes. The researchers want to find out if a c...

Recruiting

Phase: PHASE3 Conditions: Urothelial Carcinoma

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

NCT ID: NCT05039619

This clinical trial is studying a medication called obinutuzumab to see how well it works and how safe it is for adolescents aged 12 to less than 18 years who have a condition called lupus nephriti...

Recruiting

Phase: PHASE2 Conditions: Lupus Nephritis

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

NCT ID: NCT04961996

This clinical trial, called the lidERA Breast Cancer study, is looking at a new treatment called giredestrant for patients with early breast cancer that is positive for estrogen receptors and negat...

Recruiting

Phase: PHASE3 Conditions: Early Breast Cancer

Dose Optimization and Efficacy Assessment of a Fluoropyrimidine Antidote

NCT ID: NCT07032142

This clinical trial is studying a new treatment to help patients who experience serious side effects from a common chemotherapy drug called fluoropyrimidine, which is used to treat cancers like bre...

Not yet recruiting

Phase: PHASE1 Conditions: Cancer, Toxicity Due to Chemotherapy

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

NCT ID: NCT04603807

This clinical trial is investigating two medications, entrectinib and crizotinib, to see which one works better and is safer for treating patients with advanced or metastatic ROS1 non-small cell lu...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

NCT ID: NCT05268289

This clinical trial is studying a new medication called iptacopan (also known as LNP023) for patients with active lupus nephritis, a condition where the immune system attacks the kidneys. The trial...

Recruiting

Phase: PHASE2 Conditions: Lupus Nephritis

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

NCT ID: NCT04657822

This clinical trial is a rollover study for patients with Sickle Cell Disease (SCD) who have previously participated in a study sponsored by Novartis and have been receiving a medication called cri...

Recruiting

Phase: PHASE4 Conditions: Sickle Cell Disease

Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment

NCT ID: NCT06497465

This clinical trial is studying a new treatment approach for people who have both HIV and tuberculosis (TB) and have not yet received any HIV treatment. The trial is comparing two different ways of...

Not yet recruiting

Phase: PHASE3 Conditions: HIV, Tuberculosis

Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies

NCT ID: NCT05541341

This clinical trial is studying the effectiveness and safety of a treatment called tisagenlecleucel for patients in Brazil who have certain types of blood cancers, specifically Diffuse Large B-cell...

Recruiting

Conditions: Acute Lymphoblastic Leukemia, Follicular Lymphoma +1 more

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

NCT ID: NCT05894239

This clinical trial is studying a new treatment for patients with a specific type of advanced breast cancer known as HER2-positive metastatic breast cancer. The researchers want to find out if a dr...

Recruiting

Phase: PHASE3 Conditions: Metastatic Breast Cancer

Secukinumab Open Label Roll-over Extension Protocol

NCT ID: NCT04638647

The Secukinumab Open Label Roll-over Extension Protocol is a clinical trial that aims to understand the long-term safety of a medication called secukinumab for people with autoimmune and inflammato...

Recruiting

Phase: PHASE4 Conditions: Autoimmunity, Inflammation

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

NCT ID: NCT05170204

This clinical trial is looking at the effectiveness and safety of different treatment options for patients with locally advanced, unresectable Stage III non-small cell lung cancer (NSCLC). Essentia...

Recruiting

Phase: PHASE3 Conditions: Non-Small Cell Lung Cancer

Screening Study for Participants With Malignant Tumors

NCT ID: NCT05419375

This clinical trial is looking at patients with solid tumors, specifically to analyze the tumor tissue for certain markers. These markers will help determine if participants qualify for a related c...

Recruiting

Phase: PHASE2 Conditions: Solid Tumors

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

NCT ID: NCT05639114

The SIRIUS-SLE 1 trial is a research study looking at how well two different ways of using a medication called ianalumab work for people with systemic lupus erythematosus (SLE), a condition where t...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.

NCT ID: NCT05985915

This clinical trial is investigating the long-term safety and effectiveness of a medication called ianalumab for people with Sjögren's syndrome, a condition that affects the body's ability to produ...

Recruiting

Phase: PHASE3 Conditions: Sjogrens Syndrome

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

NCT ID: NCT06084936

This clinical trial is investigating a new treatment called glofitamab for patients with relapsed or refractory mantle cell lymphoma (MCL), which means their cancer has come back or hasn't responde...

Recruiting

Phase: PHASE3 Conditions: Lymphoma

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

NCT ID: NCT06133972

This clinical trial, called the SIRIUS-SLE Extension study, is looking at the long-term safety of a treatment called ianalumab for people with systemic lupus erythematosus (SLE), a condition that c...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

NCT ID: NCT06497556

This clinical trial is studying a new treatment called divarasib for patients with advanced or metastatic non-small cell lung cancer (NSCLC) that has a specific mutation known as KRAS G12C. The goa...

Recruiting

Phase: PHASE3 Conditions: Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer

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Clinical Trials in Salvador, Ba

37 Active Trials Found in Salvador

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

Dose Optimization and Efficacy Assessment of a Fluoropyrimidine Antidote

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment

Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

Secukinumab Open Label Roll-over Extension Protocol

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Screening Study for Participants With Malignant Tumors

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer