Nctid:
NCT00000178
Payload:
{"hasResults"=>false, "derivedSection"=>{"miscInfoModule"=>{"versionHolder"=>"2024-10-28"}, "conditionBrowseModule"=>{"meshes"=>[{"id"=>"D000544", "term"=>"Alzheimer Disease"}], "ancestors"=>[{"id"=>"D003704", "term"=>"Dementia"}, {"id"=>"D001927", "term"=>"Brain Diseases"}, {"id"=>"D002493", "term"=>"Central Nervous System Diseases"}, {"id"=>"D009422", "term"=>"Nervous System Diseases"}, {"id"=>"D024801", "term"=>"Tauopathies"}, {"id"=>"D019636", "term"=>"Neurodegenerative Diseases"}, {"id"=>"D019965", "term"=>"Neurocognitive Disorders"}, {"id"=>"D001523", "term"=>"Mental Disorders"}], "browseLeaves"=>[{"id"=>"M3885", "name"=>"Alzheimer Disease", "asFound"=>"Alzheimer's Disease", "relevance"=>"HIGH"}, {"id"=>"M6904", "name"=>"Dementia", "relevance"=>"LOW"}, {"id"=>"M5204", "name"=>"Brain Diseases", "relevance"=>"LOW"}, {"id"=>"M5742", "name"=>"Central Nervous System Diseases", "relevance"=>"LOW"}, {"id"=>"M23002", "name"=>"Tauopathies", "relevance"=>"LOW"}, {"id"=>"M21558", "name"=>"Neurodegenerative Diseases", "relevance"=>"LOW"}, {"id"=>"M21836", "name"=>"Neurocognitive Disorders", "relevance"=>"LOW"}, {"id"=>"M4815", "name"=>"Mental Disorders", "relevance"=>"LOW"}, {"id"=>"M14473", "name"=>"Psychotic Disorders", "relevance"=>"LOW"}, {"id"=>"T2192", "name"=>"Familial Alzheimer Disease", "asFound"=>"Alzheimer's Disease", "relevance"=>"HIGH"}], "browseBranches"=>[{"name"=>"Nervous System Diseases", "abbrev"=>"BC10"}, {"name"=>"Behaviors and Mental Disorders", "abbrev"=>"BXM"}, {"name"=>"All Conditions", "abbrev"=>"All"}, {"name"=>"Rare Diseases", "abbrev"=>"Rare"}]}, "interventionBrowseModule"=>{"meshes"=>[{"id"=>"D011241", "term"=>"Prednisone"}], "ancestors"=>[{"id"=>"D000893", "term"=>"Anti-Inflammatory Agents"}, {"id"=>"D005938", "term"=>"Glucocorticoids"}, {"id"=>"D006728", "term"=>"Hormones"}, {"id"=>"D006730", "term"=>"Hormones, Hormone Substitutes, and Hormone Antagonists"}, {"id"=>"D045505", "term"=>"Physiological Effects of Drugs"}, {"id"=>"D018931", "term"=>"Antineoplastic Agents, Hormonal"}, {"id"=>"D000970", "term"=>"Antineoplastic Agents"}], "browseLeaves"=>[{"id"=>"M14121", "name"=>"Prednisone", "asFound"=>"Prospective", "relevance"=>"HIGH"}, {"id"=>"M4217", "name"=>"Anti-Inflammatory Agents", "relevance"=>"LOW"}, {"id"=>"M9047", "name"=>"Glucocorticoids", "relevance"=>"LOW"}, {"id"=>"M9789", "name"=>"Hormones", "relevance"=>"LOW"}, {"id"=>"M9788", "name"=>"Hormone Antagonists", "relevance"=>"LOW"}, {"id"=>"M20966", "name"=>"Antineoplastic Agents, Hormonal", "relevance"=>"LOW"}], "browseBranches"=>[{"name"=>"Anti-Inflammatory Agents", "abbrev"=>"Infl"}, {"name"=>"Antineoplastic Agents", "abbrev"=>"ANeo"}, {"name"=>"All Drugs and Chemicals", "abbrev"=>"All"}]}}, "protocolSection"=>{"designModule"=>{"phases"=>["PHASE3"], "studyType"=>"INTERVENTIONAL", "designInfo"=>{"allocation"=>"RANDOMIZED", "maskingInfo"=>{"masking"=>"DOUBLE"}, "primaryPurpose"=>"TREATMENT"}}, "statusModule"=>{"overallStatus"=>"COMPLETED", "expandedAccessInfo"=>{"hasExpandedAccess"=>false}, "statusVerifiedDate"=>"2005-02", "lastUpdateSubmitDate"=>"2005-06-23", "studyFirstSubmitDate"=>"1999-10-29", "studyFirstSubmitQcDate"=>"1999-10-29", "lastUpdatePostDateStruct"=>{"date"=>"2005-06-24", "type"=>"ESTIMATED"}, "studyFirstPostDateStruct"=>{"date"=>"1999-11-01", "type"=>"ESTIMATED"}}, "conditionsModule"=>{"keywords"=>["Alzheimer's disease", "Prednisone", "Anti-inflammatory agents"], "conditions"=>["Alzheimer Disease"]}, "referencesModule"=>{"references"=>[{"pmid"=>"10680787", "type"=>"RESULT", "citation"=>"Aisen PS, Davis KL, Berg JD, Schafer K, Campbell K, Thomas RG, Weiner MF, Farlow MR, Sano M, Grundman M, Thal LJ. A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study. Neurology. 2000 Feb 8;54(3):588-93. doi: 10.1212/wnl.54.3.588."}], "seeAlsoLinks"=>[{"url"=>"http://www.alzheimers.org", "label"=>"The Alzheimer's Disease Education and Referral (ADEAR) Center is a service of the National Institute on Aging (NIA)."}]}, "descriptionModule"=>{"briefSummary"=>"This is a randomized placebo controlled, double blind study. Patients who meet eligibility criteria and decide to participate in the study will be randomly assigned to receive either drug treatment or a placebo. Neither the patients nor the participating investigators will know who is receiving the drugs and who is receiving the placebo. Participation involves 15 outpatient clinic visits over a 68 week period. Patients take study medication at varying doses (the maximum dose is 20 mg daily), along with calcium and vitamin supplements."}, "eligibilityModule"=>{"sex"=>"ALL", "stdAges"=>["CHILD", "ADULT", "OLDER_ADULT"], "minimumAge"=>"0 years", "healthyVolunteers"=>false, "eligibilityCriteria"=>"Inclusion Criteria:\n\n* Patients with Alzheimer's disease who are in stable medical condition\n\nExclusion Criteria:\n\n* Patients with diabetes or severe osteoporosis"}, "identificationModule"=>{"nctId"=>"NCT00000178", "briefTitle"=>"Multicenter Trial of Prednisone in Alzheimer's Disease", "organization"=>{"class"=>"NIH", "fullName"=>"National Institute on Aging (NIA)"}, "officialTitle"=>"Multicenter Trial of Prednisone in Alzheimer's Disease", "orgStudyIdInfo"=>{"id"=>"IA0002"}, "secondaryIdInfos"=>[{"id"=>"3U01AG010483-08S2", "link"=>"https://reporter.nih.gov/quickSearch/3U01AG010483-08S2", "type"=>"NIH"}]}, "armsInterventionsModule"=>{"interventions"=>[{"name"=>"Prednisone", "type"=>"DRUG"}]}, "contactsLocationsModule"=>{"locations"=>[{"zip"=>"35294-0017", "city"=>"Birmingham", "state"=>"Alabama", "country"=>"United States", "facility"=>"University of Alabama, Birmingham", "geoPoint"=>{"lat"=>33.52066, "lon"=>-86.80249}}, {"zip"=>"90033", "city"=>"Los Angeles", "state"=>"California", "country"=>"United States", "facility"=>"University of Southern California", "geoPoint"=>{"lat"=>34.05223, "lon"=>-118.24368}}, {"zip"=>"92093-0949", "city"=>"San Diego", "state"=>"California", "country"=>"United States", "facility"=>"University of California, San Diego", "geoPoint"=>{"lat"=>32.71533, "lon"=>-117.15726}}, {"zip"=>"32225", "city"=>"Jacksonville", "state"=>"Florida", "country"=>"United States", "facility"=>"Mayo Clinic Jacksonville", "geoPoint"=>{"lat"=>30.33218, "lon"=>-81.65565}}, {"zip"=>"33140", "city"=>"Miami", "state"=>"Florida", "country"=>"United States", "facility"=>"University of Miami", "geoPoint"=>{"lat"=>25.77427, "lon"=>-80.19366}}, {"zip"=>"33162", "city"=>"Tampa", "state"=>"Florida", "country"=>"United States", "facility"=>"University of South Florida", "geoPoint"=>{"lat"=>27.94752, "lon"=>-82.45843}}, {"zip"=>"46202", "city"=>"Indianapolis", "state"=>"Indiana", "country"=>"United States", "facility"=>"Indiana University Alzheimer's Center", "geoPoint"=>{"lat"=>39.76838, "lon"=>-86.15804}}, {"zip"=>"66160", "city"=>"Kansas City", "state"=>"Kansas", "country"=>"United States", "facility"=>"University of Kansas Medical Center", "geoPoint"=>{"lat"=>39.11417, "lon"=>-94.62746}}, {"zip"=>"21224", "city"=>"Baltimore", "state"=>"Maryland", "country"=>"United States", "facility"=>"Johns Hopkins University", "geoPoint"=>{"lat"=>39.29038, "lon"=>-76.61219}}, {"zip"=>"55455", "city"=>"Minneapolis", "state"=>"Minnesota", "country"=>"United States", "facility"=>"University of Minnesota", "geoPoint"=>{"lat"=>44.97997, "lon"=>-93.26384}}, {"zip"=>"63110", "city"=>"St. Louis", "state"=>"Missouri", "country"=>"United States", "facility"=>"Washington University", "geoPoint"=>{"lat"=>38.62727, "lon"=>-90.19789}}, {"zip"=>"10016", "city"=>"New York", "state"=>"New York", "country"=>"United States", "facility"=>"New York University Medical Center", "geoPoint"=>{"lat"=>40.71427, "lon"=>-74.00597}}, {"zip"=>"10029", "city"=>"New York", "state"=>"New York", "country"=>"United States", "facility"=>"Mount Sinai Medical Center", "geoPoint"=>{"lat"=>40.71427, "lon"=>-74.00597}}, {"zip"=>"11032", "city"=>"New York", "state"=>"New York", "country"=>"United States", "facility"=>"Columbia Presbyterian Medical Center", "geoPoint"=>{"lat"=>40.71427, "lon"=>-74.00597}}, {"zip"=>"14620", "city"=>"Rochester", "state"=>"New York", "country"=>"United States", "facility"=>"University of Rochester", "geoPoint"=>{"lat"=>43.15478, "lon"=>-77.61556}}, {"zip"=>"10605", "city"=>"White Plains", "state"=>"New York", "country"=>"United States", "facility"=>"Burke Medical Research Institute", "geoPoint"=>{"lat"=>41.03399, "lon"=>-73.76291}}, {"zip"=>"15213", "city"=>"Pittsburgh", "state"=>"Pennsylvania", "country"=>"United States", "facility"=>"University of Pittsburgh", "geoPoint"=>{"lat"=>40.44062, "lon"=>-79.99589}}, {"zip"=>"37212-8646", "city"=>"Nashville", "state"=>"Tennessee", "country"=>"United States", "facility"=>"Vanderbilt University Medical Center", "geoPoint"=>{"lat"=>36.16589, "lon"=>-86.78444}}, {"zip"=>"75235-9070", "city"=>"Dallas", "state"=>"Texas", "country"=>"United States", "facility"=>"University of Texas", "geoPoint"=>{"lat"=>32.78306, "lon"=>-96.80667}}], "overallOfficials"=>[{"name"=>"Leon Thal, MD.", "role"=>"PRINCIPAL_INVESTIGATOR", "affiliation"=>"University of California, San Diego"}]}, "sponsorCollaboratorsModule"=>{"leadSponsor"=>{"name"=>"National Institute on Aging (NIA)", "class"=>"NIH"}}}}