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Search / Trial NCT00000376

Cognitive and Drug Therapy for Drug-Resistant Depression

Launched by UNIVERSITY OF PENNSYLVANIA · Nov 2, 1999

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Trial Information

Current as of March 22, 2025

Completed

Keywords

Adult Antidepressive Agents, Tricyclic Anxiety Disorders Cognitive Therapy Combined Modality Therapy Depression Desipramine Female Human Male Personality Disorders Pilot Projects Patient Care Team Antidepressive Agents, Tricyclic *Therapeutic Use Depression *Therapy Depression Drug Therapy Desipramine *Therapeutic Use

ClinConnect Summary

To develop an effective combined cognitive therapy (CT) plus drug treatment for patients with drug-resistant depression (DRD) (i.e., depression that is refractory to medication). To develop a manual for combined treatment for DRD that integrates three existing forms of CT (CT for depression, CT for personality disorders, and CT for anxiety disorders), and that specifies interventions for combining CT and medication when two therapists (psychotherapist and pharmacotherapist) provide the treatment. To obtain outpatient, randomized control, pilot data on the clinical value of the combined CT p...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • -
  • Patients must have:
  • • Drug-resistant depression (DRD).

Trial Officials

Karla Moras, PhD

Principal Investigator

About University Of Pennsylvania

The University of Pennsylvania, a prestigious Ivy League institution located in Philadelphia, is renowned for its commitment to advancing medical research and improving healthcare outcomes. As a clinical trial sponsor, the university leverages its extensive resources, interdisciplinary expertise, and cutting-edge facilities to conduct innovative studies across various therapeutic areas. With a focus on translating scientific discoveries into clinical applications, the University of Pennsylvania fosters collaborations among leading researchers, clinicians, and industry partners, ensuring rigorous trial design and adherence to ethical standards. Through its dedication to excellence in research and education, the university plays a pivotal role in shaping the future of medicine.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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