Search / Trial NCT00000450

Naltrexone Maintenance Treatment of Alcoholism

Launched by THE SCRIPPS RESEARCH INSTITUTE · Nov 2, 1999

Trial Information

Current as of December 26, 2024

Completed

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Meets criteria for alcohol dependence.
  • Expresses a desire to cut down or stop drinking.
  • Exclusion Criteria:
  • Currently meets criteria for dependence on substances other than alcohol.
  • History of opiate dependence or evidence of current opiate use.
  • Significant medical disorders that will increase potential risk or interfere with study participation.
  • Liver function tests more than 3 times normal or elevated bilirubin.
  • Female patients who are pregnant, nursing, or not using a reliable method of birth control.
  • Inability to understand and provide a consent form.
  • Treatment with an investigational drug during the previous month.
  • Prior treatment with naltrexone.
  • Chronic treatment with any narcotic-containing medications during the previous month.
  • Sensitivity to naltrexone as evidenced by adverse drug experiences especially with narcotic containing analgesics or opioid antagonists.
  • Current treatment with disulfiram.
  • More than 6 weeks of abstinence.
  • Meets criteria for a major psychiatric disorder and is in need of, or currently undergoing pharmacotherapy.

Trial Officials

Barbara Mason, Ph.D.

Principal Investigator

The Scripps Research Institute

About The Scripps Research Institute

The Scripps Research Institute is a renowned non-profit biomedical research organization dedicated to advancing scientific knowledge and innovation in the life sciences. With a mission to enhance human health through groundbreaking research, Scripps Research conducts pioneering studies across various fields, including drug discovery, molecular biology, and immunology. The institute fosters a collaborative environment that integrates interdisciplinary approaches and state-of-the-art technologies, aiming to translate scientific discoveries into novel therapeutic interventions. Committed to excellence in research and education, Scripps Research plays a pivotal role in shaping the future of medicine and improving patient outcomes globally.

Locations

Miami, Florida, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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