Search / Trial NCT00000488

Lipid Research Clinics Coronary Primary Prevention Trial (CPPT)

Launched by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI) · Oct 27, 1999

Trial Information

Current as of December 27, 2024

Completed

Keywords

ClinConnect Summary

BACKGROUND:

Numerous prospective epidemiologic studies have demonstrated that hypercholesterolemia is a major risk factor for atherosclerotic coronary heart disease. Research on animals indicating that the reduction of serum cholesterol prevented or reversed atherosclerosis had not been shown convincingly in humans. The Coronary Primary Prevention Trial tested the hypothesis that lowering the serum cholesterol in patients who had no existing evidence of coronary heart disease would reduce the subsequent rate of coronary heart disease in those persons.

Coronary heart disease is the leading...

Gender

MALE

Eligibility criteria

  • Men, ages 35-59. Type II hyperlipoproteinemia. Free from coronary heart disease.

Trial Officials

Francois Abboud

University of Iowa

Elizabeth Barrett-Connor

University of California, San Diego

Reagan Bradford

Oklahoma Medical Research Foundation

Marilyn Buzzard

University of Minnesota

Gerald Cooper

Centers for Disease Control and Prevention

John Farquhar

Stanford University

Ivan Frantz

University of Minnesota

Anne Goldberg

Washington University School of Medicine

Frank Ibbott

Bio-Science Laboratories

William, Insull

Baylor College of Medicine

Robert Knoop

University of Washington

Peter Kwiterovich

Johns Hopkins University

John LaRosa

George Washington University

J. Little

University of Toronto

L. Sheffield

University of Alabama at Birmingham

Dennis Sprecher

University of Cincinnati

About National Heart, Lung, And Blood Institute (Nhlbi)

The National Heart, Lung, and Blood Institute (NHLBI) is a leading component of the National Institutes of Health (NIH), dedicated to advancing research and clinical trials focused on cardiovascular, pulmonary, and hematologic diseases. With a mission to improve public health through innovative research, the NHLBI supports a wide range of studies aimed at understanding, preventing, and treating heart and lung conditions. By collaborating with academic institutions, healthcare providers, and patient communities, the NHLBI strives to translate scientific discoveries into effective clinical practices, ultimately enhancing the quality of life for individuals affected by these critical health issues.

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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