Calcium for Pre-Eclampsia Prevention (CPEP)
Launched by EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT (NICHD) · Oct 27, 1999
Trial Information
Current as of March 27, 2025
Completed
Keywords
ClinConnect Summary
BACKGROUND:
A considerable body of data has associated lower blood pressures with higher levels of dietary calcium. Epidemiologic studies, laboratory evaluations, and clinical trials have also indicated that the incidence of hypertensive disorders of pregnancy is affected similarly by calcium intake. A meta-analysis of five controlled clinical trials of calcium supplementation in pregnancy suggested a significant reduction in proteinuric pre-eclampsia of 46 percent. Several of the trials, however, suffered from 'pitfalls' in the diagnosis of pre-eclampsia, including lack of blinding, uncer...
Gender
FEMALE
Eligibility criteria
- • Nulliparous, normotensive, pregnant women.
Trial Officials
Patrick Catalano
Case Western Reserve University
Luis Curet
University of New Mexico
John Hauth
University of Alabama at Birmingham
Cynthia Morris
Oregon Health and Science University
Baha Sibai
University of Tennessee
About Eunice Kennedy Shriver National Institute Of Child Health And Human Development (Nichd)
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is a prominent research agency within the National Institutes of Health (NIH), dedicated to advancing the health and well-being of children, families, and individuals across the lifespan. NICHD supports a wide range of clinical trials and research initiatives aimed at understanding the complex biological, behavioral, and environmental factors that influence human development and health. By fostering innovative research and facilitating collaboration among scientists, healthcare professionals, and communities, NICHD plays a vital role in translating scientific discoveries into effective interventions and policies that enhance child health, reproductive health, and the prevention of diseases.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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