Nctid:
NCT00000873
Payload:
{"FullStudy"=>{"Rank"=>474740, "Study"=>{"DerivedSection"=>{"MiscInfoModule"=>{"VersionHolder"=>"December 08, 2023"}, "ConditionBrowseModule"=>{"ConditionMeshList"=>{"ConditionMesh"=>[{"ConditionMeshId"=>"D000015658", "ConditionMeshTerm"=>"HIV Infections"}]}, "ConditionAncestorList"=>{"ConditionAncestor"=>[{"ConditionAncestorId"=>"D000086982", "ConditionAncestorTerm"=>"Blood-Borne Infections"}, {"ConditionAncestorId"=>"D000003141", "ConditionAncestorTerm"=>"Communicable Diseases"}, {"ConditionAncestorId"=>"D000007239", "ConditionAncestorTerm"=>"Infections"}, {"ConditionAncestorId"=>"D000015229", "ConditionAncestorTerm"=>"Sexually Transmitted Diseases, Viral"}, {"ConditionAncestorId"=>"D000012749", "ConditionAncestorTerm"=>"Sexually Transmitted Diseases"}, {"ConditionAncestorId"=>"D000016180", "ConditionAncestorTerm"=>"Lentivirus Infections"}, {"ConditionAncestorId"=>"D000012192", "ConditionAncestorTerm"=>"Retroviridae Infections"}, {"ConditionAncestorId"=>"D000012327", "ConditionAncestorTerm"=>"RNA Virus Infections"}, {"ConditionAncestorId"=>"D000014777", "ConditionAncestorTerm"=>"Virus Diseases"}, {"ConditionAncestorId"=>"D000091662", "ConditionAncestorTerm"=>"Genital Diseases"}, {"ConditionAncestorId"=>"D000091642", "ConditionAncestorTerm"=>"Urogenital Diseases"}, {"ConditionAncestorId"=>"D000007153", "ConditionAncestorTerm"=>"Immunologic Deficiency Syndromes"}, {"ConditionAncestorId"=>"D000007154", "ConditionAncestorTerm"=>"Immune System Diseases"}]}, "ConditionBrowseLeafList"=>{"ConditionBrowseLeaf"=>[{"ConditionBrowseLeafId"=>"M9973", "ConditionBrowseLeafName"=>"Infections", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M6058", "ConditionBrowseLeafName"=>"Communicable Diseases", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M17940", "ConditionBrowseLeafName"=>"HIV Infections", "ConditionBrowseLeafAsFound"=>"HIV Infections", "ConditionBrowseLeafRelevance"=>"high"}, {"ConditionBrowseLeafId"=>"M3212", "ConditionBrowseLeafName"=>"Acquired Immunodeficiency Syndrome", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M2594", "ConditionBrowseLeafName"=>"Blood-Borne Infections", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M15248", "ConditionBrowseLeafName"=>"Sexually Transmitted Diseases", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M17623", "ConditionBrowseLeafName"=>"Sexually Transmitted Diseases, Viral", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M18330", "ConditionBrowseLeafName"=>"Lentivirus Infections", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M14716", "ConditionBrowseLeafName"=>"Retroviridae Infections", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M17212", "ConditionBrowseLeafName"=>"Virus Diseases", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M14839", "ConditionBrowseLeafName"=>"RNA Virus Infections", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M2877", "ConditionBrowseLeafName"=>"Genital Diseases", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M2876", "ConditionBrowseLeafName"=>"Urogenital Diseases", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M16045", "ConditionBrowseLeafName"=>"Syndrome", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M9889", "ConditionBrowseLeafName"=>"Immunologic Deficiency Syndromes", "ConditionBrowseLeafRelevance"=>"low"}, {"ConditionBrowseLeafId"=>"M9890", "ConditionBrowseLeafName"=>"Immune System Diseases", "ConditionBrowseLeafRelevance"=>"low"}]}, "ConditionBrowseBranchList"=>{"ConditionBrowseBranch"=>[{"ConditionBrowseBranchName"=>"Infections", "ConditionBrowseBranchAbbrev"=>"BC01"}, {"ConditionBrowseBranchName"=>"All Conditions", "ConditionBrowseBranchAbbrev"=>"All"}, {"ConditionBrowseBranchName"=>"Symptoms and General Pathology", "ConditionBrowseBranchAbbrev"=>"BC23"}, {"ConditionBrowseBranchName"=>"Urinary Tract, Sexual Organs, and Pregnancy Conditions", "ConditionBrowseBranchAbbrev"=>"BXS"}, {"ConditionBrowseBranchName"=>"Immune System Diseases", "ConditionBrowseBranchAbbrev"=>"BC20"}]}}}, "ProtocolSection"=>{"DesignModule"=>{"PhaseList"=>{"Phase"=>["Not Applicable"]}, "StudyType"=>"Interventional", "DesignInfo"=>{"DesignPrimaryPurpose"=>"Treatment", "DesignInterventionModel"=>"Parallel Assignment"}, "EnrollmentInfo"=>{"EnrollmentCount"=>"2400"}}, "StatusModule"=>{"OverallStatus"=>"Completed", "ExpandedAccessInfo"=>{"HasExpandedAccess"=>"No"}, "StatusVerifiedDate"=>"October 2013", "CompletionDateStruct"=>{"CompletionDate"=>"September 2005", "CompletionDateType"=>"Actual"}, "LastUpdateSubmitDate"=>"October 4, 2013", "StudyFirstSubmitDate"=>"November 2, 1999", "StudyFirstSubmitQCDate"=>"August 30, 2001", "LastUpdatePostDateStruct"=>{"LastUpdatePostDate"=>"October 7, 2013", "LastUpdatePostDateType"=>"Estimate"}, "StudyFirstPostDateStruct"=>{"StudyFirstPostDate"=>"August 31, 2001", "StudyFirstPostDateType"=>"Estimate"}}, "ConditionsModule"=>{"KeywordList"=>{"Keyword"=>["Nutritional Status", "HIV Seronegativity", "Infant Food"]}, "ConditionList"=>{"Condition"=>["HIV Infections"]}}, "ReferencesModule"=>{"ReferenceList"=>{"Reference"=>[{"ReferenceType"=>"background", "ReferenceCitation"=>"Kaiser M, Hagopian J, Ernestine J, Moye J, Fowler M, Nesel C. Providing access to HIV-research opportunities for disenfranchised populations. Int Conf AIDS. 1998;12:845-6 (abstract no 42358)"}]}}, "DescriptionModule"=>{"BriefSummary"=>"This study examines the effects of an infant formula containing increased calories, as compared to commercial formulas, when given during the first 6 months of life. It will examine effects on growth, disease progress, immune system, and quality of life of infected infants.\n\nHIV disease in infants often leads to nutritional deficiencies. Providing increased nutrition early in their lives may help the quality of life of children who contract HIV from their mothers.", "DetailedDescription"=>"In order to meet the optimal nutritional needs of HIV-infected infants, it is critical that nutritional intervention begin early. Early nutritional intervention may help reduce the susceptibility to or severity of primary HIV and/or opportunistic infections and add to the quality of life for children perinatally infected with HIV.\n\n[AS PER AMENDMENT 08/29/01: This study population will consist of infants from domestic sites and international sites.] In this double-blind, controlled study perinatally HIV-exposed infants less than 15 days old [AS PER AMENDMENT 08/29/01: \"less than 15 days old\" has been replaced with: less than 17 days old] at time of study entry are randomized to 1 of 2 arms to receive either concentrated formula or standard formula for 8 weeks after being stratified by gestational age: less than 37 versus greater than 37 completed weeks. At the 8-week visit using a previously determined 8:1 random allocation, 89% of singleton infants [AS PER AMENDMENT 08/29/01: from international sites] with negative HIV-specific tests are discontinued from study treatment and further follow-up. The other 11 percent of these singleton infants with negative HIV-specific tests continue study treatment with open-label standard formula until Week 28 (control group). Singleton infants with positive HIV-specific tests continue on the blinded portion of the study and receive formula as initially assigned until Week 28. For a given multiple birth, if any of the infants at the 8-week study visit are determined to be infected, all the infants from that birth continue their initial blinded treatment assignment until Week 28; if none of the infants are determined to be infected at this time, all the infants from that birth continue study treatment with open-label standard formula until Week 28. All infants assigned to receive study treatment through Week 28 continue study follow-up until 12 months of age. A subset of patients at sites with appropriate resources will participate in a substudy in which measurements of triceps and thigh skinfold thickness and circumference and thigh density DEXA scans are evaluated."}, "EligibilityModule"=>{"Gender"=>"All", "MaximumAge"=>"17 days", "MinimumAge"=>"1 day", "StdAgeList"=>{"StdAge"=>["Child"]}, "HealthyVolunteers"=>"Accepts Healthy Volunteers", "EligibilityCriteria"=>"Inclusion Criteria\n\nChildren may be eligible for this study if they:\n\nAre 1 to 17 days old. (This study has been changed. Originally, infants 1 to 15 days old were eligible for this study.)\nWeigh 4 or more pounds.\nWere born to an HIV-positive mother.\nHave a caregiver willing to measure and keep records of infant's food intake.\n\nExclusion Criteria\n\nChildren will not be eligible for this study if they:\n\nAre breast-fed.\nHave certain disorders, including the inability to feed by mouth, or a life-threatening condition.\nTake medication which affects growth."}, "IdentificationModule"=>{"NCTId"=>"NCT00000873", "BriefTitle"=>"A Study on the Effect of High-Calorie Infant Formula on Growth and Nutrition in HIV-Infected Infants", "Organization"=>{"OrgClass"=>"NIH", "OrgFullName"=>"National Institute of Allergy and Infectious Diseases (NIAID)"}, "OfficialTitle"=>"A Randomized, Double-Blind, Controlled Study of an Increased Caloric Density Infant Formula and Its Effect on Growth and Nutritional Status in HIV-Infected Infants", "OrgStudyIdInfo"=>{"OrgStudyId"=>"ACTG 247"}, "SecondaryIdInfoList"=>{"SecondaryIdInfo"=>[{"SecondaryId"=>"PACTG 247"}, {"SecondaryId"=>"ACTG 844 Substudy"}, {"SecondaryId"=>"11224", "SecondaryIdType"=>"Registry Identifier", "SecondaryIdDomain"=>"DAIDS ES"}]}}, "ArmsInterventionsModule"=>{"InterventionList"=>{"Intervention"=>[{"InterventionName"=>"Infant Formula", "InterventionType"=>"Drug"}]}}, "ContactsLocationsModule"=>{"LocationList"=>{"Location"=>[{"LocationZip"=>"35233", "LocationCity"=>"Birmingham", "LocationState"=>"Alabama", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Alabama at Birmingham - Pediatric"}, {"LocationZip"=>"36604", "LocationCity"=>"Mobile", "LocationState"=>"Alabama", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of South Alabama"}, {"LocationZip"=>"85006", "LocationCity"=>"Phoenix", "LocationState"=>"Arizona", "LocationCountry"=>"United States", "LocationFacility"=>"Phoenix Childrens Hosp"}, {"LocationZip"=>"920930672", "LocationCity"=>"La Jolla", "LocationState"=>"California", "LocationCountry"=>"United States", "LocationFacility"=>"UCSD Med Ctr / Pediatrics / Clinical Sciences"}, {"LocationZip"=>"90801", "LocationCity"=>"Long Beach", "LocationState"=>"California", "LocationCountry"=>"United States", "LocationFacility"=>"Long Beach Memorial (Pediatric)"}, {"LocationZip"=>"90033", "LocationCity"=>"Los Angeles", "LocationState"=>"California", "LocationCountry"=>"United States", "LocationFacility"=>"Los Angeles County - USC Med Ctr"}, {"LocationZip"=>"900481804", "LocationCity"=>"Los Angeles", "LocationState"=>"California", "LocationCountry"=>"United States", "LocationFacility"=>"Cedars Sinai / UCLA Med Ctr"}, {"LocationZip"=>"900951752", "LocationCity"=>"Los Angeles", "LocationState"=>"California", "LocationCountry"=>"United States", "LocationFacility"=>"UCLA Med Ctr / Pediatric"}, {"LocationZip"=>"905022004", "LocationCity"=>"Los Angeles", "LocationState"=>"California", "LocationCountry"=>"United States", "LocationFacility"=>"Harbor - UCLA Med Ctr / UCLA School of Medicine"}, {"LocationZip"=>"802181088", "LocationCity"=>"Denver", "LocationState"=>"Colorado", "LocationCountry"=>"United States", "LocationFacility"=>"Children's Hosp of Denver"}, {"LocationZip"=>"060303805", "LocationCity"=>"Farmington", "LocationState"=>"Connecticut", "LocationCountry"=>"United States", "LocationFacility"=>"Connecticut Children's Med Ctr"}, {"LocationZip"=>"06504", "LocationCity"=>"New Haven", "LocationState"=>"Connecticut", "LocationCountry"=>"United States", "LocationFacility"=>"Yale Univ Med School"}, {"LocationZip"=>"20060", "LocationCity"=>"Washington", "LocationState"=>"District of Columbia", "LocationCountry"=>"United States", "LocationFacility"=>"Howard Univ Hosp"}, {"LocationZip"=>"33311", "LocationCity"=>"Fort Lauderdale", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"North Broward Hosp District"}, {"LocationZip"=>"32610", "LocationCity"=>"Gainesville", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Florida Gainesville"}, {"LocationZip"=>"32209", "LocationCity"=>"Jacksonville", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Florida Health Science Ctr / Pediatrics"}, {"LocationZip"=>"33136", "LocationCity"=>"Miami", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Miami / Jackson Memorial Hosp"}, {"LocationZip"=>"33161", "LocationCity"=>"Miami", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Miami (Pediatric)"}, {"LocationZip"=>"32806", "LocationCity"=>"Orlando", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Arnold Palmer Hosp for Children & Women"}, {"LocationZip"=>"32503", "LocationCity"=>"Pensacola", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Sacred Heart Children's Hosp / CMS of Florida"}, {"LocationZip"=>"33404", "LocationCity"=>"Riviera Beach", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Palm Beach County Health Dept"}, {"LocationZip"=>"33606", "LocationCity"=>"Tampa", "LocationState"=>"Florida", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of South Florida"}, {"LocationZip"=>"30306", "LocationCity"=>"Atlanta", "LocationState"=>"Georgia", "LocationCountry"=>"United States", "LocationFacility"=>"Emory Univ Hosp / Pediatrics"}, {"LocationZip"=>"30912", "LocationCity"=>"Augusta", "LocationState"=>"Georgia", "LocationCountry"=>"United States", "LocationFacility"=>"Med College of Georgia"}, {"LocationZip"=>"31901", "LocationCity"=>"Columbus", "LocationState"=>"Georgia", "LocationCountry"=>"United States", "LocationFacility"=>"The Med Ctr Inc"}, {"LocationZip"=>"60612", "LocationCity"=>"Chicago", "LocationState"=>"Illinois", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Illinois College of Medicine / Pediatrics"}, {"LocationZip"=>"606143394", "LocationCity"=>"Chicago", "LocationState"=>"Illinois", "LocationCountry"=>"United States", "LocationFacility"=>"Chicago Children's Memorial Hosp"}, {"LocationZip"=>"701122699", "LocationCity"=>"New Orleans", "LocationState"=>"Louisiana", "LocationCountry"=>"United States", "LocationFacility"=>"Tulane Univ / Charity Hosp of New Orleans"}, {"LocationZip"=>"21201", "LocationCity"=>"Baltimore", "LocationState"=>"Maryland", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Maryland at Baltimore / Univ Med Ctr"}, {"LocationZip"=>"212874933", "LocationCity"=>"Baltimore", "LocationState"=>"Maryland", "LocationCountry"=>"United States", "LocationFacility"=>"Johns Hopkins Hosp - Pediatric"}, {"LocationZip"=>"021155724", "LocationCity"=>"Boston", "LocationState"=>"Massachusetts", "LocationCountry"=>"United States", "LocationFacility"=>"Children's Hosp of Boston"}, {"LocationZip"=>"01199", "LocationCity"=>"Springfield", "LocationState"=>"Massachusetts", "LocationCountry"=>"United States", "LocationFacility"=>"Baystate Med Ctr of Springfield"}, {"LocationZip"=>"48201", "LocationCity"=>"Detroit", "LocationState"=>"Michigan", "LocationCountry"=>"United States", "LocationFacility"=>"Children's Hosp of Michigan"}, {"LocationZip"=>"39213", "LocationCity"=>"Jackson", "LocationState"=>"Mississippi", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Mississippi Med Ctr"}, {"LocationZip"=>"63110", "LocationCity"=>"St Louis", "LocationState"=>"Missouri", "LocationCountry"=>"United States", "LocationFacility"=>"Washington Univ School of Medicine"}, {"LocationZip"=>"08103", "LocationCity"=>"Camden", "LocationState"=>"New Jersey", "LocationCountry"=>"United States", "LocationFacility"=>"Cooper Hosp - Univ Med Ctr / UMDNJ - New Jersey Med Schl"}, {"LocationZip"=>"089030019", "LocationCity"=>"New Brunswick", "LocationState"=>"New Jersey", "LocationCountry"=>"United States", "LocationFacility"=>"UMDNJ - Robert Wood Johnson Med School / Pediatrics"}, {"LocationZip"=>"08903", "LocationCity"=>"New Brunswick", "LocationState"=>"New Jersey", "LocationCountry"=>"United States", "LocationFacility"=>"St Peter's Med Ctr"}, {"LocationZip"=>"071032714", "LocationCity"=>"Newark", "LocationState"=>"New Jersey", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Medicine & Dentistry of New Jersey / Univ Hosp"}, {"LocationZip"=>"07103", "LocationCity"=>"Newark", "LocationState"=>"New Jersey", "LocationCountry"=>"United States", "LocationFacility"=>"Saint Joseph's Hosp and Med Ctr/UMDNJ - New Jersey Med Schl"}, {"LocationZip"=>"12208", "LocationCity"=>"Albany", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Children's Hosp at Albany Med Ctr"}, {"LocationZip"=>"10457", "LocationCity"=>"Bronx", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Bronx Lebanon Hosp Ctr"}, {"LocationZip"=>"11203", "LocationCity"=>"Brooklyn", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"SUNY - Brooklyn"}, {"LocationZip"=>"11021", "LocationCity"=>"Great Neck", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"North Shore Univ Hosp"}, {"LocationZip"=>"10016", "LocationCity"=>"New York", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Bellevue Hosp / New York Univ Med Ctr"}, {"LocationZip"=>"10021", "LocationCity"=>"New York", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Cornell Univ Med College"}, {"LocationZip"=>"10029", "LocationCity"=>"New York", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Metropolitan Hosp Ctr"}, {"LocationZip"=>"10032", "LocationCity"=>"New York", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Columbia Presbyterian Med Ctr"}, {"LocationZip"=>"10037", "LocationCity"=>"New York", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Harlem Hosp Ctr"}, {"LocationZip"=>"146420001", "LocationCity"=>"Rochester", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Rochester Med Ctr"}, {"LocationZip"=>"117948111", "LocationCity"=>"Stony Brook", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"State Univ of New York at Stony Brook"}, {"LocationZip"=>"13210", "LocationCity"=>"Syracuse", "LocationState"=>"New York", "LocationCountry"=>"United States", "LocationFacility"=>"SUNY Health Sciences Ctr at Syracuse / Pediatrics"}, {"LocationZip"=>"277103499", "LocationCity"=>"Durham", "LocationState"=>"North Carolina", "LocationCountry"=>"United States", "LocationFacility"=>"Duke Univ Med Ctr"}, {"LocationZip"=>"27710", "LocationCity"=>"Durham", "LocationState"=>"North Carolina", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of North Carolina at Chapel Hill / Duke Univ Med Ctr"}, {"LocationZip"=>"432052696", "LocationCity"=>"Columbus", "LocationState"=>"Ohio", "LocationCountry"=>"United States", "LocationFacility"=>"Columbus Children's Hosp"}, {"LocationZip"=>"294253312", "LocationCity"=>"Charleston", "LocationState"=>"South Carolina", "LocationCountry"=>"United States", "LocationFacility"=>"Med Univ of South Carolina"}, {"LocationZip"=>"29203", "LocationCity"=>"Columbia", "LocationState"=>"South Carolina", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of South Carolina School of Med"}, {"LocationZip"=>"75235", "LocationCity"=>"Dallas", "LocationState"=>"Texas", "LocationCountry"=>"United States", "LocationFacility"=>"Children's Med Ctr of Dallas"}, {"LocationZip"=>"77030", "LocationCity"=>"Houston", "LocationState"=>"Texas", "LocationCountry"=>"United States", "LocationFacility"=>"Texas Children's Hosp / Baylor Univ"}, {"LocationZip"=>"78284", "LocationCity"=>"San Antonio", "LocationState"=>"Texas", "LocationCountry"=>"United States", "LocationFacility"=>"Univ of Texas Health Sciences Ctr"}, {"LocationZip"=>"23219", "LocationCity"=>"Richmond", "LocationState"=>"Virginia", "LocationCountry"=>"United States", "LocationFacility"=>"Med College of Virginia"}, {"LocationZip"=>"981050371", "LocationCity"=>"Seattle", "LocationState"=>"Washington", "LocationCountry"=>"United States", "LocationFacility"=>"Children's Hospital & Medical Center / Seattle ACTU"}, {"LocationCity"=>"Nassau", "LocationCountry"=>"Bahamas", "LocationFacility"=>"Princess Margaret Hosp"}, {"LocationCity"=>"Belo Horizonte-MG", "LocationCountry"=>"Brazil", "LocationFacility"=>"Federal University of Minas, Dept. of Pediatrics"}, {"LocationCity"=>"Rio de Janeiro RJ", "LocationCountry"=>"Brazil", "LocationFacility"=>"Hosp Univ Clementino Fraga Filho"}, {"LocationCity"=>"Rio de Janeiro", "LocationCountry"=>"Brazil", "LocationFacility"=>"Hosp dos Servidores do Estado"}, {"LocationZip"=>"00956", "LocationCity"=>"Bayamon", "LocationCountry"=>"Puerto Rico", "LocationFacility"=>"Ramon Ruiz Arnau Univ Hosp / Pediatrics"}, {"LocationZip"=>"00726", "LocationCity"=>"Caguas", "LocationCountry"=>"Puerto Rico", "LocationFacility"=>"Caguas Regional Hosp"}, {"LocationZip"=>"00680", "LocationCity"=>"Mayguez", "LocationCountry"=>"Puerto Rico", "LocationFacility"=>"Mayguez Med Ctr / Regional Immunology Clinic"}, {"LocationZip"=>"00731", "LocationCity"=>"Ponce", "LocationCountry"=>"Puerto Rico", "LocationFacility"=>"Ponce Univ Hosp"}, {"LocationZip"=>"009365067", "LocationCity"=>"San Juan", "LocationCountry"=>"Puerto Rico", "LocationFacility"=>"Univ of Puerto Rico / Univ Children's Hosp AIDS"}, {"LocationZip"=>"009367344", "LocationCity"=>"San Juan", "LocationCountry"=>"Puerto Rico", "LocationFacility"=>"San Juan City Hosp"}]}, "OverallOfficialList"=>{"OverallOfficial"=>[{"OverallOfficialName"=>"Harland S Winter", "OverallOfficialRole"=>"Study Chair"}, {"OverallOfficialName"=>"James Oleske", "OverallOfficialRole"=>"Study Chair"}, {"OverallOfficialName"=>"Ross McKinney", "OverallOfficialRole"=>"Study Chair"}]}}, "SponsorCollaboratorsModule"=>{"LeadSponsor"=>{"LeadSponsorName"=>"National Institute of Allergy and Infectious Diseases (NIAID)", "LeadSponsorClass"=>"NIH"}, "CollaboratorList"=>{"Collaborator"=>[{"CollaboratorName"=>"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "CollaboratorClass"=>"NIH"}]}, "ResponsibleParty"=>{"ResponsiblePartyType"=>"Sponsor"}}}}}}
