Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family History of Cross-Eye

Launched by NATIONAL EYE INSTITUTE (NEI) · Nov 3, 1999

Keywords

ClinConnect Summary

Little is known about the development of the ocular motor system in children. We hypothesize that quantitative analysis of "at risk" infants eye movement systems can detect abnormalities that precede and predict the onset of strabismus. We will collect data on the eye movements of a group of infants born between 36 and 44 weeks of post-conceptual age. These infants are enrolled between 4 and 24 weeks after birth and followed at 4 week (+/-5 days) intervals until 28 weeks of age and then yearly until 3 years after birth. After study enrollment infants will undergo a complete ophthalmic evalu...

Gender

ALL

Eligibility criteria

• • Participants must have a gestational age at birth between 36-42 weeks and birth weight greater than or equal to 2500 gms.
• • Participants must have normal growth and development as assessed by general pediatric examination and growth charts, obtained historically from family and/or pediatrician.
• • Participants must have a normal visual system by ophthalmic examination.
• • Participants must be between the post-conceptual ages of 40 weeks and 70 weeks of age inclusive.
• • Participants must be able to undergo a complete opthalmic evaluation.
• • Participants must be able to undergo standard eye movement recording.
• • Participants must not have any eye diseases.
• • Participants must not have any neurologic disease, developmental delay, congenital genetic syndromes, congenital organ malformations, malformation syndromes or metabolic diseases.
• • Participants must not be on any systemic or ocular medications.