Nctid:
NCT00001164
Payload:
{"hasResults"=>false, "derivedSection"=>{"miscInfoModule"=>{"versionHolder"=>"2024-10-21"}, "conditionBrowseModule"=>{"meshes"=>[{"id"=>"D000014777", "term"=>"Virus Diseases"}, {"id"=>"D000009136", "term"=>"Muscular Dystrophies"}, {"id"=>"D000012162", "term"=>"Retinal Degeneration"}, {"id"=>"D000012871", "term"=>"Skin Diseases"}], "ancestors"=>[{"id"=>"D000020966", "term"=>"Muscular Disorders, Atrophic"}, {"id"=>"D000009135", "term"=>"Muscular Diseases"}, {"id"=>"D000009140", "term"=>"Musculoskeletal Diseases"}, {"id"=>"D000009468", "term"=>"Neuromuscular Diseases"}, {"id"=>"D000009422", "term"=>"Nervous System Diseases"}, {"id"=>"D000030342", "term"=>"Genetic Diseases, Inborn"}, {"id"=>"D000007239", "term"=>"Infections"}, {"id"=>"D000015785", "term"=>"Eye Diseases, Hereditary"}, {"id"=>"D000005128", "term"=>"Eye Diseases"}, {"id"=>"D000012164", "term"=>"Retinal Diseases"}], "browseLeaves"=>[{"id"=>"M15674", "name"=>"Skin Diseases", "asFound"=>"Skin Diseases", "relevance"=>"HIGH"}, {"id"=>"M12093", "name"=>"Muscular Dystrophies", "asFound"=>"Muscular Dystrophy", "relevance"=>"HIGH"}, {"id"=>"M17522", "name"=>"Virus Diseases", "asFound"=>"Virus Disease", "relevance"=>"HIGH"}, {"id"=>"M14997", "name"=>"Retinal Degeneration", "asFound"=>"Retinal Degeneration", "relevance"=>"HIGH"}, {"id"=>"M4589", "name"=>"Atrophy", "relevance"=>"LOW"}, {"id"=>"M12092", "name"=>"Muscular Diseases", "relevance"=>"LOW"}, {"id"=>"M22697", "name"=>"Muscular Disorders, Atrophic", "relevance"=>"LOW"}, {"id"=>"M12097", "name"=>"Musculoskeletal Diseases", "relevance"=>"LOW"}, {"id"=>"M12411", "name"=>"Neuromuscular Diseases", "relevance"=>"LOW"}, {"id"=>"M23686", "name"=>"Genetic Diseases, Inborn", "relevance"=>"LOW"}, {"id"=>"M10283", "name"=>"Infections", "relevance"=>"LOW"}, {"id"=>"M6368", "name"=>"Communicable Diseases", "relevance"=>"LOW"}, {"id"=>"M8271", "name"=>"Eye Diseases", "relevance"=>"LOW"}, {"id"=>"M18339", "name"=>"Eye Diseases, Hereditary", "relevance"=>"LOW"}, {"id"=>"M14999", "name"=>"Retinal Diseases", "relevance"=>"LOW"}, {"id"=>"T3963", "name"=>"Muscular Dystrophy", "asFound"=>"Muscular Dystrophy", "relevance"=>"HIGH"}], "browseBranches"=>[{"name"=>"Skin and Connective Tissue Diseases", "abbrev"=>"BC17"}, {"name"=>"All Conditions", "abbrev"=>"All"}, {"name"=>"Musculoskeletal Diseases", "abbrev"=>"BC05"}, {"name"=>"Nervous System Diseases", "abbrev"=>"BC10"}, {"name"=>"Diseases and Abnormalities at or Before Birth", "abbrev"=>"BC16"}, {"name"=>"Infections", "abbrev"=>"BC01"}, {"name"=>"Eye Diseases", "abbrev"=>"BC11"}, {"name"=>"Symptoms and General Pathology", "abbrev"=>"BC23"}, {"name"=>"Rare Diseases", "abbrev"=>"Rare"}]}}, "protocolSection"=>{"designModule"=>{"studyType"=>"OBSERVATIONAL"}, "statusModule"=>{"overallStatus"=>"COMPLETED", "startDateStruct"=>{"date"=>"1978-07"}, "expandedAccessInfo"=>{"hasExpandedAccess"=>false}, "statusVerifiedDate"=>"2000-06", "completionDateStruct"=>{"date"=>"2000-06"}, "lastUpdateSubmitDate"=>"2008-03-04", "studyFirstSubmitDate"=>"1999-11-03", "studyFirstSubmitQcDate"=>"2002-12-09", "lastUpdatePostDateStruct"=>{"date"=>"2008-03-05", "type"=>"ESTIMATED"}, "studyFirstPostDateStruct"=>{"date"=>"2002-12-10", "type"=>"ESTIMATED"}}, "conditionsModule"=>{"keywords"=>["Genetic Evaluation", "Immunologic Evaluations", "Inflammatory Skin Disease", "Muscular Dystrophies", "Neoplastic Skin Diseases", "Neuronal Degenerations", "Retinal Degenerations", "Viral Diseases"], "conditions"=>["Healthy", "Muscular Dystrophy", "Retinal Degeneration", "Skin Diseases", "Virus Diseases"]}, "referencesModule"=>{"references"=>[{"pmid"=>"164028", "type"=>"BACKGROUND", "citation"=>"Kraemer KH, Coon HG, Petinga RA, Barrett SF, Rahe AE, Robbins JH. Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc Natl Acad Sci U S A. 1975 Jan;72(1):59-63. doi: 10.1073/pnas.72.1.59."}, {"pmid"=>"972257", "type"=>"BACKGROUND", "citation"=>"Yaoita H, Katz SI. Immunoelectronmicroscopic localization of IgA in skin of patients with dermatitis herpetiformis. J Invest Dermatol. 1976 Oct;67(4):502-6. doi: 10.1111/1523-1747.ep12664534."}]}, "descriptionModule"=>{"briefSummary"=>"It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.", "detailedDescription"=>"It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate."}, "eligibilityModule"=>{"sex"=>"ALL", "stdAges"=>["CHILD", "ADULT", "OLDER_ADULT"], "healthyVolunteers"=>true, "eligibilityCriteria"=>"Patients with skin diseases of presumed genetic, immunologic, or virologic origin are eligible.\n\nPatients with neurological degenerations are eligible, including patients with inflammatory, neoplastic and viral skin diseases and also heterozygous carriers of such inherited diseases.\n\nVolunteers without skin diseases are eligible, except children."}, "identificationModule"=>{"nctId"=>"NCT00001164", "briefTitle"=>"Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers", "organization"=>{"class"=>"NIH", "fullName"=>"National Institutes of Health Clinical Center (CC)"}, "officialTitle"=>"Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers", "orgStudyIdInfo"=>{"id"=>"780099"}, "secondaryIdInfos"=>[{"id"=>"78-C-0099"}]}, "contactsLocationsModule"=>{"locations"=>[{"zip"=>"20892", "city"=>"Bethesda", "state"=>"Maryland", "country"=>"United States", "facility"=>"National Cancer Institute (NCI)", "geoPoint"=>{"lat"=>38.98067, "lon"=>-77.10026}}]}, "sponsorCollaboratorsModule"=>{"leadSponsor"=>{"name"=>"National Cancer Institute (NCI)", "class"=>"NIH"}}}}
