Current as of March 05, 2024
Gyrate atrophy of the choroid and retina (GA) is a rare autosomal recessive chorioretinal degeneration characterized by myopia, cataract, varying degrees of night blindness, and progressive constriction of visual fields associated with chorioretinal atrophy resulting in blindness. The objectives of this protocol are threefold: Document the natural history of gyrate atrophy. Relate the clinical course to the gene defect to explore the genetic heterogeneity inherent in this disease. Assess the clinical course and laboratory findings of the effects of an arginine-deficient diet. The study pop...
- INCLUSION CRITERIA:
- Patients must have hyperornithemia and a deficiency of OAT activity to enter the study.
The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, United States
All reviews come from applied patients