The Treatment of Grade I Sarcomas and Benign, Non-Metastasizing Highly Invasive Soft Tissue Tumors
Launched by NATIONAL CANCER INSTITUTE (NCI) · Dec 9, 2002
Trial Information
Current as of December 10, 2023
Completed
Keywords
Description
This is a randomized study. Patients undergo surgical excision of all gross disease and then are randomized to Arm I or Arm II. Arm I: Radiotherapy. Involved-field irradiation. Arm II: No further treatment.
Gender
All
Eligibility criteria
- DISEASE CHARACTERISTICS:
- Biopsy-proven grade I soft tissue sarcoma or one of the following benign but highly invasive soft tissue tumors:
- Abdominal and extra-abdominal fibromatosis (desmoid,
- aggressive fibromatosis),
- Dermatofibrosarcoma protuberans,
- Intramuscular lipoma (infiltrating lipoma),
- Diffuse lipomatosis,
- Leiomyoma of deep soft tissue,
- Diffuse giant cell tumor of tendon sheath (proliferative synovitis).
- No clinical evidence of metastases in regional nodes or more distant sites.
- No primary intraperitoneal or retroperitoneal tumors.
- Resection of all gross tumor at the time of surgical excision required (margins may be pathologically positive or negative).
- No von Recklinghausen's disease.
- PRIOR/CONCURRENT THERAPY:
- Biologic Therapy: Not specified.
- Chemotherapy: No prior chemotherapy for sarcoma.
- Endocrine Therapy: Not specified.
- Radiotherapy: No prior radiotherapy for sarcoma.
- Surgery: No more than 4 months since definitive surgery for
- primary lesion or recurrence.
- No prior amputation.
- PATIENT CHARACTERISTICS:
- Age: 18 and over.
- Performance status: Not specified.
- Hematopoietic: Not specified.
- Hepatic: No cirrhosis.
- Renal: No evidence of severe renal impairment.
- Cardiovascular: No ischemic heart disease.
- OTHER:
- No prior malignancy except basal cell carcinoma.
- No serious infection.
- No active bleeding disorder.
- No severe concomitant disease.
Attachments
4.5 MB
4.5 MB
About company
The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bethesda, Maryland, United States
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Reviews (48)
All reviews come from applied patients

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?
Discussion 0