Search / Trial NCT00001245

Study of Patients With Strongyloides Stercoralis Infection

Launched by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID) · Nov 3, 1999

Trial Information

Current as of November 04, 2024

Completed

Keywords

Strongyloidiasis Immediate Hypersensitivity Skin Test Ig E Nematode Immunosuppression Skin Test Diagnosis Intestinal Helminth Immediate Hypersensitivity

ClinConnect Summary

This study is directed to patients with known or suspected Strongyloides stercoralis infection because it is a relatively common parasitic infection, even in the United States. It is difficult to diagnose, and efficacy of treatment is difficult to evaluate. Some infected individuals can develop serious even fatal, disease under certain conditions of immunosuppression. Because newer diagnostic methods are needed to diagnose this infection, we have developed new diagnostics that will be evaluated in comparison to more standard diagnostic tests. Serum and cells will also be collected from pati...

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • Age of 5 to 80 years and of either sex.
  • Access to primary medical care provider outside of the NIH
  • Ability to give written informed consent (for adults) and parental consent (for those under 18)
  • Presence of known or suspected infection with Stronglyloides stercoralis, such as significant peripheral blood eosinophilia (greater than 1000 eosinophils/mm(3)) for which no other cause is apparent.
  • Willingness to participate and provide blood for in vitro assays and serum storage.
  • EXCLUSION CRITERIA:
  • Less than 5 years of age
  • Pregnancy is not a criterion for exclusion.

About National Institute Of Allergy And Infectious Diseases (Niaid)

The National Institute of Allergy and Infectious Diseases (NIAID) is a key component of the National Institutes of Health (NIH) dedicated to advancing the understanding, prevention, and treatment of infectious and immune-mediated diseases. Through rigorous clinical trials, NIAID aims to foster innovative research that enhances public health and addresses global health challenges, including emerging infectious diseases and allergies. The institute collaborates with various partners, including academic institutions, industry, and international organizations, to translate scientific discoveries into effective therapies and vaccines. NIAID's commitment to high-quality clinical research is integral to improving health outcomes and informing policy decisions in the realm of infectious diseases and immunology.

Locations

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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