Search / Trial NCT00001360

Studies of Blood Flow to the Brain During Thought

Launched by NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH) · Nov 3, 1999

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Trial Information

Current as of December 26, 2024

Recruiting

Keywords

Cognition Vision Cortex Visual Processing Magnetic Resonance Imaging Natural History

ClinConnect Summary

This clinical trial is looking at how blood flows to different parts of the brain while people think and perform various tasks. Researchers will use a special brain imaging technique called functional magnetic resonance imaging (fMRI) to see how the brain reacts when participants engage in activities related to seeing, recognizing, and remembering things. The goal is to better understand how our brains work during these intellectual tasks.

To take part in this study, participants need to be healthy adults aged 18 to 65 years who have at least a high school education. However, those with certain medical conditions, serious head injuries, or specific vision and hearing problems won't be eligible. During the study, participants can expect to spend some time in the fMRI machine while completing tasks that challenge their thinking. It's important to note that anyone who is pregnant or has metal implants may not be able to participate due to safety concerns with the imaging process. This study is currently looking for volunteers, so if you're interested and meet the criteria, you could help contribute to our understanding of brain functions!

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • • Healthy adults, with at least a high school education, aged 18 to 65 years, will be recruited to participate in the study.
  • EXCLUSION CRITERIA:
  • Subjects will be excluded if they:
  • • are an NIMH employee or a relative
  • * have evidence of, or a history of:
  • • major medical, neurological or psychiatric illness
  • • serious head injury
  • • learning disability-drug or alcohol abuse or dependence in the past 3 months, except nicotine
  • • -are taking prescription drugs or supplements that may affect brain function-
  • • -have serious vision or hearing problems
  • In addition to the above, additional exclusion criteria apply for all MRI studies:
  • • Female subjects who are pregnant or have a positive pregnancy test 24 hours prior to an experiment will be excluded from neuroimaging studies.
  • • All subjects will be questioned prior to MRI scanning for possible occupational exposure to metal slivers or shavings, which may have become accidentally lodged in the tissues of the head or neck. Subjects with surgical clips or shrapnel in or near the brain or blood vessels, subjects with cochlear implants, subjects with any metallic body in the eye or CNS, and subjects with any form of implant wire or metal device which may concentrate radiofrequency fields will be excluded from MRI scanning experiments because of possible risks during MRI scanning. Those whose history is suggestive of such a problem will also be excluded from the MRI portion of the experiments. They may still participate in the behavioral and MEG experiments.
  • • Subjects unable to lie flat on their back for up to 2 hours may not be eligible to participate in MRI scans.

Trial Officials

Alex Martin, Ph.D.

Principal Investigator

National Institute of Mental Health (NIMH)

About National Institute Of Mental Health (Nimh)

The National Institute of Mental Health (NIMH) is a leading federal agency dedicated to advancing the understanding and treatment of mental health disorders through innovative research and clinical trials. As part of the National Institutes of Health (NIH), NIMH focuses on a broad spectrum of mental health issues, including mood disorders, anxiety disorders, schizophrenia, and developmental disorders. By fostering collaboration among researchers, clinicians, and the community, NIMH aims to translate scientific discoveries into effective interventions and improve mental health outcomes for individuals across the lifespan. Through its commitment to rigorous research methodologies and ethical standards, NIMH plays a pivotal role in shaping the future of mental health care and policy.

Locations

Bethesda, Maryland, United States

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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