Using X-Ray Dye to Locate Hidden Parathyroid Tumors

Launched by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) · Nov 3, 1999

Keywords

ClinConnect Summary

Although noninvasive diagnostic studies \[ultrasound (US), computed tomography (CT), sestamibi scanning, magnetic resonance imaging (MRI)\] detect parathyroid pathology in one-half the patients referred to NIH with recurrent or persistent hyperparathyroidism (1), the invasive studies (direct aspiration for PTH, arteriography, venous sampling) must be performed in the remaining patients to provide definitive preoperative localization (2). Arteriography is positive in less than half the patients who must then proceed to parathyroid venous sampling, a technique requiring broad experience and y...

Gender

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Eligibility criteria

• INCLUSION CRITERIA:
• • Patients over the age of 2 who are enrolled in 91-DK-0085, "Studies of Hyperparathyroidism and Related Disorders", or patients who are undergoing parathyroid localization as part of routine patient care while enrolled in other Clinical protocols will be considered for the study.
• EXCLUSION CRITERIA:
• Patients will be excluded if:
• • There is any contraindication to arteriography.
• • The Patient is pregnant.