Search / Trial NCT00001459

Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers

Launched by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI) · Dec 9, 2002

Trial Information

Current as of December 08, 2024

Completed

Keywords

Gated Blood Pool Spect Scan Coronary Artery Disease Hypertrophic Cardiomyopathy Microvascular Angina

ClinConnect Summary

We propose to assess regional myocardial function using gated blood pool imaging acquired by a tomographic technique at rest and during stress in patients with myocardial ischemia (coronary artery disease, hypertrophic cardiomyopathy and microvascular angina). Gender differences in response to exercise and pharmacologic stress will also be evaluated. Normal subjects will be studied in order to establish a control database. Current methods of gated blood pool studies use planar imaging, with its attendant limitations; poor resolution and inadequate separation of the myocardial segments, only...

Gender

ALL

Eligibility criteria

  • Patients with known coronary artery disease (obstruction of greater than or equal to 50% in at least one major coronary artery).
  • Patients with hypertrophic cardiomyopathy.
  • Patients with microvascular angina.
  • No unstable angina.
  • No hepatic or renal failure.
  • Infective endocarditis
  • No primary valvular disease.
  • No congenital heart disease.
  • No pregnant or breast feeding women.

About National Heart, Lung, And Blood Institute (Nhlbi)

The National Heart, Lung, and Blood Institute (NHLBI) is a leading component of the National Institutes of Health (NIH), dedicated to advancing research and clinical trials focused on cardiovascular, pulmonary, and hematologic diseases. With a mission to improve public health through innovative research, the NHLBI supports a wide range of studies aimed at understanding, preventing, and treating heart and lung conditions. By collaborating with academic institutions, healthcare providers, and patient communities, the NHLBI strives to translate scientific discoveries into effective clinical practices, ultimately enhancing the quality of life for individuals affected by these critical health issues.

Locations

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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