Outcomes of Education and Counseling for BRCA1 Testing

Launched by NATIONAL HUMAN GENOME RESEARCH INSTITUTE (NHGRI) · Dec 9, 2002

Keywords

ClinConnect Summary

Women at increased risk for developing breast and/or ovarian cancer and their first degree relatives will be offered BRCA1/2 gene testing. This study proposes to evaluate psychological and behavioral aspects of their decision-making and the outcomes of the testing process. Knowledge and expectations will be assessed initially, followed by pre-test psychological assessment and an in person education and counseling session. Participants will be presented the choice of whether or not to undergo BRCA1/2 testing. Notification of test results will occur in person along with discussion of availabl...

Gender

ALL

Eligibility criteria

• • Participants will be drawn from the families enrolled by Drs. Peggy Tucker and Jeff Struewing in the GEB of NCI (protocol 78-C-0039).
• • Individual with a family history of verified breast and/or ovarian cancer that includes;
• • 1. two cases of ovarian cancer in first degree relatives, or
• • 2. three cases of breast cancer and at least one case of ovarian cancer (two of which have to be first degree relatives), or
• • 3. at least four cases of breast cancer.