Trials
Search / Trial NCT00001468

Outcomes of Education and Counseling for BRCA1 Testing

Launched by NATIONAL HUMAN GENOME RESEARCH INSTITUTE (NHGRI) · Dec 9, 2002

Trial Information

Current as of January 15, 2025

Completed

Keywords

Behavioral And Attitudinal Changes Breast Cancer High Risk Families Inherited Susceptibility Psychological Responses To Risk

ClinConnect Summary

Women at increased risk for developing breast and/or ovarian cancer and their first degree relatives will be offered BRCA1/2 gene testing. This study proposes to evaluate psychological and behavioral aspects of their decision-making and the outcomes of the testing process. Knowledge and expectations will be assessed initially, followed by pre-test psychological assessment and an in person education and counseling session. Participants will be presented the choice of whether or not to undergo BRCA1/2 testing. Notification of test results will occur in person along with discussion of availabl...

Gender

ALL

Eligibility criteria

  • Participants will be drawn from the families enrolled by Drs. Peggy Tucker and Jeff Struewing in the GEB of NCI (protocol 78-C-0039).
  • Individual with a family history of verified breast and/or ovarian cancer that includes;
  • 1. two cases of ovarian cancer in first degree relatives, or
  • 2. three cases of breast cancer and at least one case of ovarian cancer (two of which have to be first degree relatives), or
  • 3. at least four cases of breast cancer.

About National Human Genome Research Institute (Nhgri)

The National Human Genome Research Institute (NHGRI) is a prominent research organization within the National Institutes of Health (NIH) dedicated to advancing the field of genomics and its applications in health and medicine. NHGRI sponsors and conducts a wide range of clinical trials aimed at understanding the genetic basis of diseases, developing innovative genomic technologies, and translating genomic research into clinical practice. With a commitment to ethical research and collaboration, NHGRI plays a pivotal role in shaping the future of personalized medicine and improving patient outcomes through genomic discoveries.

Locations

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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