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Search / Trial NCT00001546

Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers

Launched by NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH) · Dec 9, 2002

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Trial Information

Current as of March 18, 2025

Completed

Keywords

Biochemical Screening Body Temperature Consent Form Eeg Ekg Melatonin Mood Physical Examination Psychiatric Examination Sleep Duration Sleep Disorders

ClinConnect Summary

Habitual sleep duration varies greatly among individuals. The biological meaning of this variation is unknown. The present project proposes that differences in habitual sleep duration are associated with differences in the output of the endogenous circadian pacemaker, which programs the 'internal biological night'. The protocol hypothesizes that the duration of the internal biological night as defined by the nocturnal intervals of detectable plasma melatonin levels, low body temperature, low EEG activity in the high-frequency alpha band, increasing sleepiness and increasing plasma cortisol ...

Gender

ALL

Eligibility criteria

  • • Sleep greater than or equal to 9 hours almost every night.
  • • Sleep less than or equal to 6 hours almost every night.
  • • Between ages 20-30.
  • • No medications, history of psychiatric illness, history of head injury.
  • • No sleep disturbances.

About National Institute Of Mental Health (Nimh)

The National Institute of Mental Health (NIMH) is a leading federal agency dedicated to advancing the understanding and treatment of mental health disorders through innovative research and clinical trials. As part of the National Institutes of Health (NIH), NIMH focuses on a broad spectrum of mental health issues, including mood disorders, anxiety disorders, schizophrenia, and developmental disorders. By fostering collaboration among researchers, clinicians, and the community, NIMH aims to translate scientific discoveries into effective interventions and improve mental health outcomes for individuals across the lifespan. Through its commitment to rigorous research methodologies and ethical standards, NIMH plays a pivotal role in shaping the future of mental health care and policy.

Locations

Bethesda, Maryland, United States

People applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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