Search / Trial NCT00001610

Normal Human Electro-Oculogram

Launched by NATIONAL EYE INSTITUTE (NEI) · Nov 3, 1999

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Trial Information

Current as of December 10, 2023

Completed

Keywords

Standing Potential Fast Oscillation Slow Oscillation Retinal Pigment Epithelium Electro Oculogram Cellular Immune Response Retinal Antigens Irbp S Antigen Normal Volunteer

Description

Electro-oculograms (EOGs) will be recorded in volunteers of different age groups with normal visual function. The fast and slow oscillations of the EOG will be studied. For the analysis of fast EOG oscillations, peak-to-peak amplitude (micro V), peak-to-trough ratio, and phase (degrees) will be measured. The analysis of slow EOG oscillations will include measurements of the ratio of light peak to dark trough (Arden ratio), implicit time (latency) of the light peak (ms), and amplitude of the dark trough (micro V).

Gender

All

Eligibility criteria

  • Subjects must have best corrected visual acuity equal or better than 20/20.
  • Subjects must have normal visual fields.
  • Subjects must have normal color vision.
  • Subjects must have a normal ophthalmological exam.
  • Subjects should not be subjective to or objective evidence of visual loss.
  • Subjects cannot have subjective evidence of abnormal night vision or subjective evidence of abnormal light sensitivity.
  • Subjects cannot have a personal history of non-trivial ocular disease.
  • Subjects cannot have a family history of hereditary ocular disease.
  • Subjects cannot have current systemic disease.
  • Subjects cannot currently take neuropharmacological medication.
  • Subjects will not be admitted with an abnormal ophthalmological examination.
  • Subjects will need the ability to cooperate with EOG recording.

Attachments

readout_NCT00001610_2023-12-10.pdf

4.5 MB

NCT00001610_study_protocol.pdf

4.5 MB

About company

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Reviews (48)

4.6

All reviews come from applied patients

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Leslie Alexander
20 September 2023

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Michael Foster
20 September 2023

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Dries Vincent
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Leslie Alexander
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

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