Normal Human Electro-Oculogram

Launched by NATIONAL EYE INSTITUTE (NEI) · Nov 3, 1999

Keywords

ClinConnect Summary

Electro-oculograms (EOGs) will be recorded in volunteers of different age groups with normal visual function. The fast and slow oscillations of the EOG will be studied. For the analysis of fast EOG oscillations, peak-to-peak amplitude (micro V), peak-to-trough ratio, and phase (degrees) will be measured. The analysis of slow EOG oscillations will include measurements of the ratio of light peak to dark trough (Arden ratio), implicit time (latency) of the light peak (ms), and amplitude of the dark trough (micro V).

Gender

ALL

Eligibility criteria

• • Subjects must have best corrected visual acuity equal or better than 20/20.
• • Subjects must have normal visual fields.
• • Subjects must have normal color vision.
• • Subjects must have a normal ophthalmological exam.
• • Subjects should not be subjective to or objective evidence of visual loss.
• • Subjects cannot have subjective evidence of abnormal night vision or subjective evidence of abnormal light sensitivity.
• • Subjects cannot have a personal history of non-trivial ocular disease.
• • Subjects cannot have a family history of hereditary ocular disease.
• • Subjects cannot have current systemic disease.
• • Subjects cannot currently take neuropharmacological medication.
• • Subjects will not be admitted with an abnormal ophthalmological examination.
• • Subjects will need the ability to cooperate with EOG recording.