Nctid:
NCT00001746
Payload:
{"hasResults"=>false, "derivedSection"=>{"miscInfoModule"=>{"versionHolder"=>"2024-09-05"}, "conditionBrowseModule"=>{"meshes"=>[{"id"=>"D000006331", "term"=>"Heart Diseases"}, {"id"=>"D000009202", "term"=>"Cardiomyopathies"}, {"id"=>"D000002312", "term"=>"Cardiomyopathy, Hypertrophic"}, {"id"=>"D000006984", "term"=>"Hypertrophy"}], "ancestors"=>[{"id"=>"D000002318", "term"=>"Cardiovascular Diseases"}, {"id"=>"D000020763", "term"=>"Pathological Conditions, Anatomical"}, {"id"=>"D000001020", "term"=>"Aortic Stenosis, Subvalvular"}, {"id"=>"D000001024", "term"=>"Aortic Valve Stenosis"}, {"id"=>"D000082862", "term"=>"Aortic Valve Disease"}, {"id"=>"D000006349", "term"=>"Heart Valve Diseases"}], "browseLeaves"=>[{"id"=>"M9419", "name"=>"Heart Diseases", "asFound"=>"Heart Disease", "relevance"=>"HIGH"}, {"id"=>"M12154", "name"=>"Cardiomyopathies", "asFound"=>"Cardiomyopathy", "relevance"=>"HIGH"}, {"id"=>"M5568", "name"=>"Cardiomyopathy, Hypertrophic", "asFound"=>"Hypertrophic Cardiomyopathy", "relevance"=>"HIGH"}, {"id"=>"M10035", "name"=>"Hypertrophy", "asFound"=>"Hypertrophic", "relevance"=>"HIGH"}, {"id"=>"M22519", "name"=>"Pathological Conditions, Anatomical", "relevance"=>"LOW"}, {"id"=>"M4340", "name"=>"Aortic Valve Stenosis", "relevance"=>"LOW"}, {"id"=>"M6475", "name"=>"Constriction, Pathologic", "relevance"=>"LOW"}, {"id"=>"M2379", "name"=>"Aortic Valve Disease", "relevance"=>"LOW"}, {"id"=>"M9437", "name"=>"Heart Valve Diseases", "relevance"=>"LOW"}, {"id"=>"T449", "name"=>"Aortic Valve Stenosis", "relevance"=>"LOW"}], "browseBranches"=>[{"name"=>"Heart and Blood Diseases", "abbrev"=>"BC14"}, {"name"=>"All Conditions", "abbrev"=>"All"}, {"name"=>"Symptoms and General Pathology", "abbrev"=>"BC23"}, {"name"=>"Rare Diseases", "abbrev"=>"Rare"}]}}, "protocolSection"=>{"designModule"=>{"studyType"=>"OBSERVATIONAL"}, "statusModule"=>{"overallStatus"=>"COMPLETED", "startDateStruct"=>{"date"=>"1998-04"}, "expandedAccessInfo"=>{"hasExpandedAccess"=>false}, "statusVerifiedDate"=>"2003-04", "completionDateStruct"=>{"date"=>"2003-04"}, "lastUpdateSubmitDate"=>"2008-03-04", "studyFirstSubmitDate"=>"1999-11-03", "studyFirstSubmitQcDate"=>"1999-11-03", "lastUpdatePostDateStruct"=>{"date"=>"2008-03-05", "type"=>"ESTIMATED"}, "studyFirstPostDateStruct"=>{"date"=>"1999-11-04", "type"=>"ESTIMATED"}}, "conditionsModule"=>{"keywords"=>["Hypertrophic Cardiomyopathy", "HCM", "Evaluation for Research", "Medical Advice"], "conditions"=>["Heart Disease", "Hypertrophic Cardiomyopathy"]}, "referencesModule"=>{"references"=>[{"pmid"=>"3547130", "type"=>"BACKGROUND", "citation"=>"Maron BJ, Bonow RO, Cannon RO 3rd, Leon MB, Epstein SE. Hypertrophic cardiomyopathy. Interrelations of clinical manifestations, pathophysiology, and therapy (1). N Engl J Med. 1987 Mar 26;316(13):780-9. doi: 10.1056/NEJM198703263161305. No abstract available."}, {"pmid"=>"7671349", "type"=>"BACKGROUND", "citation"=>"Wigle ED, Rakowski H, Kimball BP, Williams WG. Hypertrophic cardiomyopathy. Clinical spectrum and treatment. Circulation. 1995 Oct 1;92(7):1680-92. doi: 10.1161/01.cir.92.7.1680."}, {"pmid"=>"1975599", "type"=>"BACKGROUND", "citation"=>"Solomon SD, Jarcho JA, McKenna W, Geisterfer-Lowrance A, Germain R, Salerni R, Seidman JG, Seidman CE. Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease. J Clin Invest. 1990 Sep;86(3):993-9. doi: 10.1172/JCI114802."}]}, "descriptionModule"=>{"briefSummary"=>"Genetically inherited heart diseases like hypertrophic cardiomyopathy (HCM) are conditions affecting the heart passed on to family members by abnormalities in genetic information. These conditions are responsible for many heart related deaths and illnesses.\n\nPresently, there are several research studies being conducted in order to improve the understanding of disease processes and symptoms associated with genetically inherited heart diseases.\n\nThis study is designed to determine the eligibility of patients diagnosed with or suspected to have inherited heart disease to participate in these research studies.", "detailedDescription"=>"Patients with hypertrophic cardiomyopathy (HCM) and other inherited cardiac diseases are being studied under several research protocols to determine their pathogenesis and clinical manifestations. The purpose of this protocol is to determine the eligibility of patients with known or suspected inherited heart conditions for our research protocols."}, "eligibilityModule"=>{"sex"=>"ALL", "stdAges"=>["CHILD", "ADULT", "OLDER_ADULT"], "healthyVolunteers"=>false, "eligibilityCriteria"=>"INCLUSION CRITERIA\n\nSubjects and family members known or suspected to have inherited a cardiac disease such as HCM.\n\nEXCLUSION CRITERIA\n\nPatients with cardiac conditions that are not known to be inherited."}, "identificationModule"=>{"nctId"=>"NCT00001746", "briefTitle"=>"Screening for Inherited Heart Disease", "organization"=>{"class"=>"NIH", "fullName"=>"National Institutes of Health Clinical Center (CC)"}, "officialTitle"=>"Evaluation of Patients With Known or Suspected Inherited Heart Disease (Screening Protocol)", "orgStudyIdInfo"=>{"id"=>"980102"}, "secondaryIdInfos"=>[{"id"=>"98-H-0102"}]}, "contactsLocationsModule"=>{"locations"=>[{"zip"=>"20892", "city"=>"Bethesda", "state"=>"Maryland", "country"=>"United States", "facility"=>"National Heart, Lung and Blood Institute (NHLBI)", "geoPoint"=>{"lat"=>38.98067, "lon"=>-77.10026}}]}, "sponsorCollaboratorsModule"=>{"leadSponsor"=>{"name"=>"National Heart, Lung, and Blood Institute (NHLBI)", "class"=>"NIH"}}}}
