Search / Trial NCT00002262

A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Aug 30, 2001

Trial Information

Current as of December 26, 2024

Completed

Keywords

Skin Neoplasms Tumor Necrosis Factor Acquired Immunodeficiency Syndrome

ClinConnect Summary

No description provided

Gender

MALE

Eligibility criteria

  • Inclusion Criteria
  • Patients must have:
  • Biopsy-proven Kaposi's sarcoma (KS) with multiple cutaneous lesions.
  • Minimum life expectancy of 3 months.
  • Exclusion Criteria
  • Co-existing Condition:
  • Patients with the following conditions or symptoms are excluded:
  • Clinically significant cardiac disease.
  • Known hemorrhagic diathesis or active bleeding disorder.
  • Clinically apparent vascular disease.
  • Known lipoprotein disorders.
  • History of seizure disorder or central nervous system (CNS) metastasis.
  • Additional malignancy.
  • Concurrent Medication:
  • Excluded:
  • Cardiac agents.
  • Anticoagulants.
  • Thrombolytic agents.
  • Nonsteroidal anti-inflammatory drugs.
  • Corticosteroids.
  • Aspirin.
  • Vasodilators.
  • Patients with the following are excluded:
  • Additional malignancies or other conditions listed in Patient Exclusion Co-Existing Conditions.
  • Prior Treatment:
  • Excluded within 4 weeks of study entry:
  • Chemotherapy.
  • Radiotherapy.
  • Immunotherapy.

About University Of California, San Francisco

The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.

Locations

San Francisco, California, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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