A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

Launched by GLAXO WELLCOME · Aug 30, 2001

Keywords

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Gender

ALL

Eligibility criteria

• • Exclusion Criteria
• Co-existing Condition:
• • Patients with current life-threatening infection at time of transplant that would preclude a transplant are excluded.
• Concurrent Medication:
• Excluded:
• • Other anti-retroviral agents.
• • Patients with current life-threatening infection at time of transplant that would preclude a transplant are excluded.
• Patients must be:
• • HTLV III antibody positive by ELISA or Western blot or HTLV III viremia.
• • At high mortal risk with a diagnosis of AIDS or AIDS Related Complex (ARC).
• * Also patient must fall into one of the following categories:
• • Have an HIV seronegative identical twin to serve as a bone marrow donor.
• • Have documentation of large cell/diffuse histiocytic lymphoma/DPDL.
• • Be a good risk candidate for bone marrow transplant.