MRI and CT Scans to Evaluate Invasive Cervical Cancer Before Treating Patients
Launched by AMERICAN COLLEGE OF RADIOLOGY IMAGING NETWORK · Jan 26, 2003
Trial Information
Current as of June 10, 2025
Completed
Keywords
ClinConnect Summary
OBJECTIVES:
* Compare the diagnostic performance of magnetic resonance imaging (MRI), computed tomography (CT), and clinical FIGO staging in patients with invasive cervical cancer.
* Compare the accuracy of MRI, CT, and clinical FIGO staging in the evaluation of morphologic tumor prognostic factors in FIGO stage IB1 and stage IB2 and greater in these patients.
* Examine the value of imaging assessment of tumor prognostic factors (alone or in combination) as predictors of recurrence within 2 years of surgery in these patients.
* Evaluate the quality of life in the 12-month period after stag...
Gender
FEMALE
Eligibility criteria
- DISEASE CHARACTERISTICS:
- • Histologically confirmed invasive cervical cancer, including invasive squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma
- • FIGO stage IB1 with clinically visible gross lesion OR
- • FIGO stage IB2 or greater
- * Scheduled for one of the following surgeries at a participating Gynecological Oncology Group center:
- • Laparoscopic, transabdominal, or transvaginal hysterectomy
- • Extrafascial total abdominal hysterectomy
- • Trachelectomy
- • Not scheduled for a loop electrosurgical excision procedure or a cone biopsy only
- PATIENT CHARACTERISTICS:
- Age:
- • Not specified
- Performance status:
- • Not specified
- Life expectancy:
- • Not specified
- Hematopoietic:
- • Not specified
- Hepatic:
- • Not specified
- Renal:
- • Not specified
- Cardiovascular:
- • No cardiac pacemakers
- Pulmonary:
- • No asthma
- Other:
- • Not pregnant
- • No contraindication to computed tomography (CT) (e.g., history of allergy to CT contrast medium)
- • No contraindication to magnetic resonance imaging (e.g., intracranial vascular clip)
- • No nonmalignant general medical or psychiatric condition that would preclude consent or surgery
- PRIOR CONCURRENT THERAPY:
- Biologic therapy:
- • Not specified
- Chemotherapy:
- • No prior chemotherapy
- Endocrine therapy:
- • Not specified
- Radiotherapy:
- • No prior radiotherapy for invasive cervical cancer
- Surgery:
- • See Disease Characteristics
- • No prior surgery for invasive cervical cancer
- Other:
- • No prior medical treatment for invasive cervical cancer
About American College Of Radiology Imaging Network
The American College of Radiology Imaging Network (ACRIN) is a prominent clinical trial sponsor dedicated to advancing the field of medical imaging through rigorous research and innovation. As a leader in the development and implementation of imaging-related clinical trials, ACRIN focuses on enhancing the quality and efficacy of diagnostic imaging practices. The organization collaborates with academic institutions, healthcare providers, and industry partners to facilitate multicenter studies that address critical questions in radiology, ultimately aiming to improve patient care and outcomes. Through its commitment to evidence-based research, ACRIN plays a pivotal role in shaping the future of radiologic sciences.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
New York, New York, United States
Morristown, New Jersey, United States
Patients applied
Trial Officials
Hedvig Hricak, MD, PhD
Study Chair
Memorial Sloan Kettering Cancer Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials