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Search / Trial NCT00146172

Study Evaluating HKI-272 in Tumors

Launched by PUMA BIOTECHNOLOGY, INC. · Sep 2, 2005

Trial Information

Current as of May 02, 2025

Completed

Keywords

Tumors Neratinib Hki 272 Nerlynx

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Her2/neu or Her1/EGFR positive cancer
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
  • Measurable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST)
  • Exclusion Criteria:
  • Prior treatment with anthracyclines with a cumulative dose of doxorubicin or equivalent of greater than 300 mg/m\^2
  • Patients with significant cardiac risk factors
  • Active central nervous system metastasis

About Puma Biotechnology, Inc.

Puma Biotechnology, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of cancer. Leveraging advanced scientific research, Puma is dedicated to addressing unmet medical needs by bringing to market targeted therapies that aim to improve patient outcomes. With a robust pipeline of investigational drugs, the company is committed to clinical excellence and collaboration with healthcare professionals to enhance the lives of patients living with cancer.

Locations

Saint Louis, Missouri, United States

Boston, Massachusetts, United States

Tampa, Florida, United States

Nashville, Tennessee, United States

Cleveland, Ohio, United States

Patients applied

0 patients applied

Trial Officials

Puma

Study Director

Biotechnology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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