Mutation Screening and Translocation Detection of DISC1 Gene in Schizophrenia
Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Sep 9, 2005
Trial Information
Current as of May 10, 2025
Completed
Keywords
ClinConnect Summary
The grant proposal has two major research goals. The first goal will be constructing an E.coli plasmid carried with an approximately 1.4 kb of DNA sequences from each 700 bps of the chromosome 1q42.1 and 11q14.3 around the breakpoint. The second goal will be establishing the denaturing high performance liquid chromatography (DHPLC) methods to screen the mutations or polymorphisms for all the exons of DISC1 gene, the 1 kb at the promoter region, and the sequences from 1 kb at the upstream and downstream of the breakpoint.
Translocation (1q42.1;11q14.3)-Carried Plasmid DNA Construction
Huma...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Schizophrenia
- • Chinese Han People
- Exclusion Criteria:
- • -
About National Taiwan University Hospital
National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Hai-Gwo Hwu, Professor
Principal Investigator
National Taiwan University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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