"Cuffed Versus Uncuffed Tracheal Tubes in Small Children"
Launched by UNIVERSITY CHILDREN'S HOSPITAL, ZURICH · Sep 13, 2005
Trial Information
Current as of May 15, 2025
Completed
Keywords
ClinConnect Summary
The use of cuffed tracheal tubes is a controversial topic in paediatric anaesthesia and intensive care medicine. Cuffed tubes have traditionally been recommended for children older than 8 to 10 years. During the past decade, however, several authors have argued for the use of cuffed tracheal tubes in younger children and infants. A frequently cited argument against their use is the fear from post-extubation morbidity, allegedly caused by cuff induced tracheal and laryngeal airway injury. Using modern improved designed cuffed tracheal tubes, data from randomised prospective studies, performe...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Children aged from birth (weighing \> 3 kg) to \<5 years
- • Children requiring oro-tracheal or naso-tracheal intubation with a Magil shaped tracheal tube or preformed (RAE) tracheal tube as a part of their anaesthetic care and planed IPPV during the surgical / interventional / diagnostic procedure
- • Tracheal intubation performed using direct laryngoscopy
- • Extubation after the procedure in the OR theatre
- • Procedure performed in supine position
- • Patients for elective and emergency surgery and/or interventions if there is no risk for regurgitation or pulmonary aspiration
- • ASA I and II patients
- • Written parental consent
- Exclusion Criteria:
- • No parental written consent obtained
- • Known airway anomalies (airway stenosis, including Down's Syndrome)
- • Known or suspected difficult intubation
- • Known need for abnormal tube size
- • Full stomach and/or at risk for regurgitation
- • Surgery of the larynx and/or of the trachea and/or neck and/or upper oesophagus
- • Pulmonary diseases (concurrent pneumonia or bronchial infection, asthma requiring inhalation medication, pulmonary malformations)
- • ASA class III and higher
- • Fiberoptic intubation or alternative intubation technique
- • Patients planned for postoperative ventilation in the ICU
- • Weight and/or height percentiles \< 3% / \> 97%
About University Children's Hospital, Zurich
The University Children's Hospital Zurich is a leading academic medical institution dedicated to advancing pediatric healthcare through innovative research and clinical excellence. Affiliated with the University of Zurich, the hospital specializes in a wide range of pediatric disciplines, offering comprehensive care to children and adolescents. As a prominent sponsor of clinical trials, the institution is committed to exploring new therapies and improving treatment protocols, ensuring that young patients benefit from the latest advancements in medicine. With a focus on collaboration, the hospital engages in partnerships with researchers, healthcare professionals, and pharmaceutical companies to drive impactful studies that enhance the health and well-being of children globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Innsbruck, , Austria
Brussels, , Belgium
Prague, , Czech Republic
Augsburg, , Germany
Berlin, , Germany
Berlin, , Germany
Hannover, , Germany
Loerrach, , Germany
Mannheim, , Germany
München, , Germany
Regensburg, , Germany
Bratislava, , Slovakia
Kosice, , Slovakia
Stockholm, , Sweden
Zurich, Zh, Switzerland
Aarau, , Switzerland
Bern, , Switzerland
Geneva, , Switzerland
Lausanne, , Switzerland
St. Gallen, , Switzerland
Aberdeen, , United Kingdom
Glasgow, , United Kingdom
Leeds, , United Kingdom
London, , United Kingdom
Patients applied
Trial Officials
Markus Weiss, Prof MD
Principal Investigator
University Children's Hospital, Anesthesiology
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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