Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema
Launched by UNIVERSITY HOSPITAL, BASEL, SWITZERLAND · Oct 5, 2005
Trial Information
Current as of June 03, 2025
Terminated
Keywords
ClinConnect Summary
Background Pleural empyema has a high morbidity and mortality. Until now it is not clear which method is best to initially drain the pus, especially in complicated effusions with septa.
The objective of this study is to compare the standard treatment of simple chest tube drainage to early mini-invasive medical thoracoscopy. In earlier studies medical thoracoscopy has been a safe and effective method in pleural diseases. However there is no prospective data available.
Methods We conduct a prospective randomized controlled multicenter study on 100 patients with complicated parapneumonic eff...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Septated pleural effusion (ultrasonography) in the context of a lower respiratory tract infection
- • Frank pleural empyema (pus)
- Exclusion Criteria:
- • Fibrothorax
- • Tuberculous empyema
- • Medical thoracoscopy cannot be performed within 24 hours
- • Pregnancy
- • Inability to give informed consent
About University Hospital, Basel, Switzerland
The University Hospital Basel, Switzerland, is a leading academic medical center renowned for its commitment to cutting-edge research and innovative patient care. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise and state-of-the-art facilities to advance medical knowledge and therapeutic options across various disciplines. With a collaborative approach that integrates clinical practice and scientific inquiry, the University Hospital Basel fosters an environment conducive to rigorous clinical trials, ensuring the highest standards of safety and efficacy. Its strategic focus on patient-centered research aims to translate scientific discoveries into tangible health solutions, benefiting both local and global communities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Alexandroupolis, , Greece
Brescia, , Italy
Imperia, , Italy
Parma, , Italy
Crans Montana, , Switzerland
Patients applied
Trial Officials
Martin H Brutsche, MD, Prof.
Principal Investigator
Pneumology, Kantonsspital St. Gallen
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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