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Search / Trial NCT00237276

Experience and Enhancement: Improving Colonoscopic Polyp Detection

Launched by LONDON NORTH WEST HEALTHCARE NHS TRUST · Oct 10, 2005

Trial Information

Current as of May 16, 2025

Unknown status

Keywords

Colonoscopy, Chromoendoscopy, Autoflurescence, Narrow Band Imaging, High Definition Endoscopy, Colorectal Cancer, Colitis, Polyp, Dalm, Adenoma, Video

ClinConnect Summary

Colorectal cancer is the second commonest cause of cancer death. In a majority of cases it is preceeded by a precancerous lesion called an adenoma (commonly known as polyp). Patients with colitis are at specially high risk of colorectal cancer which is estimated to be 18% at 30 years of disease. Detection and removal of adenomas at colonoscopy has been shown to reduce the death rate from colorectal cancer. However, despite meticulous examination there is a "miss rate" for adenomas at colonoscopy with ranges from 6-15% in back-to-back colonoscopy studies. The nature of the polyps which as we...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients: over 18 years of age, with clinical indication for colonoscopy who are considered by the endoscopist to be fit for the procedure
  • Endoscopists who have started colonoscopy training on a recognised training rotation. Consultants who perform colonoscopy regularly
  • Exclusion Criteria:
  • patients under 18 years, patients with previous colorectal surgery or known familial polyposis, patients unable to give informed consent, pregnant patients, patients for whom coloscope insertion was difficult or uncomfortable, patients whose colon is not sufficiently cleared of stool, those unwilling to participate

About London North West Healthcare Nhs Trust

London North West Healthcare NHS Trust is a leading healthcare provider in the UK, dedicated to delivering high-quality patient care across a diverse range of medical services. With a commitment to innovation and research, the Trust actively engages in clinical trials to advance medical knowledge and improve treatment outcomes. It operates several hospitals and community services, serving a large and diverse population in North West London. By fostering collaboration between healthcare professionals and researchers, London North West Healthcare NHS Trust aims to enhance patient care through evidence-based practices and the integration of cutting-edge medical research into clinical settings.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Brian Saunders, MD, FRCP

Principal Investigator

London North West Healthcare NHS Trust

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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