Effectiveness and Safety Study of Etomidate Versus Midazolam to Help Place a Breathing Tube Outside of the Hospital.
Launched by ST. LUKE'S HOSPITAL, PENNSYLVANIA · Nov 2, 2005
Trial Information
Current as of June 18, 2025
Completed
Keywords
ClinConnect Summary
Study Objective: The objective of this study was to compare the utility of etomidate and midazolam for sedative facilitated intubation (SFI), without paralytics, in pre-hospital adult patients.
Methods: This prospective, double-blind, randomized trial was conducted with two ground pre-hospital Advanced Life Support (ALS) units. All patients age 18 or over transported by the two participating systems requiring pre-hospital SFI were eligible for participation. The ambulances were stocked with blinded numbered syringes, each containing either 7mg of midazolam or 20mg of etomidate. Contact wit...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Under the study protocol, all patients age 18 or over transported by the two participating ALS systems, requiring pre-hospital Sedation Facilitated Intubation, were eligible for participation.
- Exclusion Criteria:
- • Exclusion criteria were pregnancy and age less than 18.
About St. Luke's Hospital, Pennsylvania
St. Luke's Hospital in Pennsylvania is a leading healthcare institution committed to advancing medical knowledge and patient care through innovative clinical research. As a prominent sponsor of clinical trials, St. Luke's Hospital focuses on a wide range of therapeutic areas, leveraging its state-of-the-art facilities and a team of experienced healthcare professionals to ensure the highest standards of research integrity and participant safety. With a dedication to improving health outcomes, St. Luke's collaborates with pharmaceutical companies, academic institutions, and healthcare organizations to facilitate groundbreaking studies that contribute to the development of new treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bethlehem, Pennsylvania, United States
Patients applied
Trial Officials
Jeanne L Jacoby, MD
Principal Investigator
St. Luke's Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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