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Search / Trial NCT00251966

ASTERIX: Low Dose ASA and Nexium

Launched by ASTRAZENECA · Nov 9, 2005

Trial Information

Current as of May 29, 2025

Completed

Keywords

Prevention Of Gastroduodenal Lesions Erosive Oesophagitis Upper Gi Symptoms

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • A clinical diagnosis of a condition (cardiovascular and/or cerebrovascular protection or other reasons) that requires daily intake of low-dose ASA, 75-325 mg, and is expected to continue for the duration of the study (daily is defined as at least 5 days per week).
  • Age \>= 60 years.
  • No gastric and/or duodenal ulcer at the baseline endoscopy.
  • H. pylori negative by serology test at screening.
  • Exclusion Criteria:
  • Upper GI symptoms
  • Erosive oesophagitis
  • Malignancy

About Astrazeneca

AstraZeneca is a global biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines across various therapeutic areas, including oncology, cardiovascular, respiratory, and autoimmune diseases. With a strong commitment to scientific research and patient-centric solutions, AstraZeneca leverages cutting-edge technology and a robust pipeline to address unmet medical needs. The company collaborates with healthcare professionals, academic institutions, and other organizations to advance clinical trials and deliver transformative therapies, aiming to improve health outcomes and enhance the quality of life for patients worldwide.

Locations

Edmonton, Alberta, Canada

Halifax, Nova Scotia, Canada

Hamilton, Ontario, Canada

London, Ontario, Canada

Toronto, Ontario, Canada

Budapest, , Hungary

Debrecen, , Hungary

Mainz, Rheinland Pfalz, Germany

Hamburg, , Germany

Mainz, , Germany

Cape Town, , South Africa

Lyttelton Manor, , South Africa

Parktown, , South Africa

Edinburgh, , United Kingdom

Pleven, , Bulgaria

Russe, , Bulgaria

Sofia, , Bulgaria

Varna, , Bulgaria

Quebec, , Canada

Wiesbaden, , Germany

Athens, , Greece

Ioannina, , Greece

Thessaloniki, , Greece

Hong Kong, , Hong Kong

Madrid, , Spain

Glasgow, , United Kingdom

Winnipeg, Manitoba, Canada

St. John's, Newfoundland And Labrador, Canada

Frankfurt, , Germany

Sudbury, Ontario, Canada

Cottbus, Brandenburg, Germany

Düsseldorf, Nordrhein Westfalen, Germany

Köln, , Germany

München, , Germany

Parma, Pr, Italy

Napoli, , Italy

Roma, , Italy

Sevilla, , Spain

Tygerberg, , South Africa

Ashford, South Australia, Australia

Hannover, , Germany

Granada, , Spain

Piraeus, , Greece

Gyula, , Hungary

Malvern, Victoria, Australia

Adelaide, , Australia

Bologna, , Italy

Kecskemét, , Hungary

Cardiff, , United Kingdom

Burgas, , Bulgaria

Potsdam, , Germany

Santiago De Compostela, A Coruña, Spain

North York, Ontario, Canada

Thornhill, Ontario, Canada

Ludwigshafen, , Germany

Oelde, , Germany

Ribnitz Damgarten, , Germany

Wolmirstedt, , Germany

Stuttgart, Baden Württemberg, Germany

Hannover, Niedersachsen, Germany

Halle, Sachsen Anhalt, Germany

Eger, , Hungary

Santiago, A Coruña, Spain

San Sebastián, Guipuzcoa, Spain

Gy¿R, , Hungary

Künzing, , Germany

Genova, Ge, Italy

Bay Roberts, Newfoundland And Labrador, Canada

Carbonear, Newfoundland And Labrador, Canada

Courcelette, Quebec, Canada

Miskolc, , Hungary

Oakville, Ontario, Canada

Parkdale, Prince Edward Island, Canada

Herne, , Germany

Lienen, , Germany

Lüdenscheid, , Germany

Münster, , Germany

Paderborn, , Germany

Wangen, , Germany

Vác, , Hungary

Carina Heights, Queensland, Australia

Murcia, , Spain

Woodville, South Australia, Australia

Bondi Junction, New South Wales, Australia

Bracken Ridge, Queensland, Australia

Wayville, South Australia, Australia

Ballarat, Victoria, Australia

Rostock, Mecklenburg Vorpommern, Germany

Siegen, , Germany

Wolfenbüttel, , Germany

Zeven, , Germany

Johannesurg, , South Africa

Irvine, Ayrshire, United Kingdom

Patients applied

0 patients applied

Trial Officials

AstraZeneca Nexium Medical Science Director, MD

Study Director

AstraZeneca

Neville Yeomans, MD

Principal Investigator

Perth Medical School

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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