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Search / Trial NCT00253812

Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy

Launched by LONDON NORTH WEST HEALTHCARE NHS TRUST · Nov 11, 2005

Trial Information

Current as of June 12, 2025

Unknown status

Keywords

Colonoscopy, Sigmoidoscopy, Chromoendoscopy, Autofluorescence, Narrow Band Imaging, Colorectal Cancer, Polyp, Adenoma,Rectal Remnant, Fap

ClinConnect Summary

Colorectal cancer is the second commonest cause of cancer death. In majority of cases it is preceeded by a precancerous lesion called an adenoma (commonly known as polyp). Detection and removal of adenomas has been shown to reduce the death rate from colorectal cancer. Despite of meticulous examination "a miss rate" for adenomas at colonoscopy ranges from 6-15% in back-to-back colonoscopy studies. The nature of the polyps, which as well as being pedunculated (cherry like) can also be flat, which makes it difficult to see and detect and may add to the"miss rate".

The factors that affect whe...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with Familial adenomatous polyposis who have had ileo-rectal anastomosis and had 20 or less adenomas at previous surveillance examination
  • Exclusion Criteria:
  • poor bowel preparation, unable or unwilling to give informed consent, under 18 years of age,those with more than 20 adenoma

About London North West Healthcare Nhs Trust

London North West Healthcare NHS Trust is a leading healthcare provider in the UK, dedicated to delivering high-quality patient care across a diverse range of medical services. With a commitment to innovation and research, the Trust actively engages in clinical trials to advance medical knowledge and improve treatment outcomes. It operates several hospitals and community services, serving a large and diverse population in North West London. By fostering collaboration between healthcare professionals and researchers, London North West Healthcare NHS Trust aims to enhance patient care through evidence-based practices and the integration of cutting-edge medical research into clinical settings.

Locations

London, Middlesex, United Kingdom

Patients applied

0 patients applied

Trial Officials

Brian Saunders, MD, FRCP

Study Director

Nort West London Hospitals NHS Trust - St Mark's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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