Safety Study of Membrane Sweeping in Pregnancy
Launched by TRIPLER ARMY MEDICAL CENTER · Feb 17, 2006
Trial Information
Current as of June 10, 2025
Completed
Keywords
ClinConnect Summary
The question of routine membrane sweeping and prelabor rupture of membranes has not been specifically addressed in a randomized control trial. A meta analysis of membrane sweeping found ten publications which analyzed this question as a secondary outcome, though none of these studies sought to analyze PROM in their objectives. This meta analysis found the relative risk of prelabor rupture of membranes to be 1.14 with membrane sweeping, however the confidence interval was 0.89 to 1.45 making the finding not significant. Despite this, we feel that a study to specifically address this issue is...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Uncomplicated, singleton pregnancies
- • candidates for vaginal delivery
- • 38 to 42 weeks estimated gestational age
- Exclusion Criteria:
- • multiple gestation
- • placenta previa
- • placental abruption
- • pre-gestational or gestational diabetes
- • chronic or gestational hypertension
- • pre-eclampsia
- • pregnancy before 38 weeks gestation
- • any pregnancy with an indication for induction other than impending post dates
- • any pregnancy not planning of vaginal delivery
- • history or preterm labor or prelabor rupture of membranes
- • vasa previa
- • cervical dilation 3cm or greater upon entry to study
- • active cervical infection
- • third trimester vaginal bleeding
- • significant maternal mullerian anomalies
- • severe fetal anomalies
- • active genital herpes infection
About Tripler Army Medical Center
Tripler Army Medical Center (TAMC) is a premier military medical facility located in Honolulu, Hawaii, dedicated to delivering high-quality healthcare to active-duty service members, their families, and veterans. As a key sponsor of clinical trials, TAMC is committed to advancing medical research and improving patient outcomes through innovative studies and evidence-based practices. The center collaborates with various military and civilian organizations to facilitate research that addresses critical health issues, supports the well-being of the Armed Forces, and contributes to the broader medical community. With a focus on ethical standards and patient safety, TAMC plays a vital role in enhancing the understanding of treatments and interventions in diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tamc, Hawaii, United States
Tripler Amc, Hawaii, United States
Patients applied
Trial Officials
Micah J Hill, D.O.
Principal Investigator
United States Army
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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