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Search / Trial NCT00353002

A Comparison of Amethocaine Cream vs. Liposomal Lidocaine Cream for Venipuncture in Children.

Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · Jul 14, 2006

Trial Information

Current as of June 10, 2025

Withdrawn

Keywords

Pain Ametop Liposomal Lidocaine Venous Cannulation

ClinConnect Summary

Children commonly require blood taking or placement of an intravenous line for both diagnosis and treatment during their visit to the emergency department. The distress from needle puncture is a particular issue in children. The development of needle phobia can subsequently adversely affect the well-being of the children and their relationship with the medical staff. Thus reduction of pain and distress would be beneficial to patients, parents, and medical personnel.

Amethocaine (tetracaine 4%) (Ametop) is another topical anaesthetic cream which was marketed in Canada over the last 10 years...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All children age who are visiting the paediatric emergency department and need for IV cannulation or blood workup as part of their management. The need for IV placement or blood drawing will be based on the clinical evaluation of the child by experienced triage nursing personnel.
  • Exclusion Criteria:
  • Lack of parental agreement
  • Broken skin
  • Known sensitivity to Amethocaine or Liposomal Lidocaine cream.
  • Children with critical illness requiring immediate cannulation (e.g., sepsis, severe dehydration, Trauma)
  • Children who are already receiving opioid analgesia or topical anesthesia.
  • Children who have already participated in the study.

About London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's

The London Health Sciences Centre Research Institute, affiliated with Lawson Health Research Institute at St. Joseph's Health Care, is dedicated to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into practical applications, the institute fosters collaboration among leading researchers, clinicians, and healthcare professionals. It aims to improve patient outcomes and enhance the quality of care through rigorous investigation in areas such as cancer, cardiovascular health, and neuroscience. By integrating cutting-edge research with clinical practice, the institute plays a pivotal role in shaping the future of healthcare delivery in the community and beyond.

Locations

London, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Michael J Rieder, MD PhD FRCPC

Principal Investigator

Children's Hospital of Western Ontario, University of Western Ontario

Khalid Alawi, MD FRCPC

Study Director

Children's Hospital of Western Ontario

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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