Exercise in Chronically Paced Children
Launched by EMORY UNIVERSITY · Sep 8, 2006
Trial Information
Current as of May 25, 2025
Completed
Keywords
ClinConnect Summary
In third degree, or complete atrioventricular (AV) block, atrial electrical impulses fail to conduct to the ventricles. Congenital complete AV block (CCAVB) has an incidence of 1 in 15,000 to 1 in 25,000 live births and has a strong association with maternal antibodies. Patients with isolated CCAVB range from completely asymptomatic to experiencing syncope, exercise intolerance or congestive heart failure. A portion of the symptoms attributable to CCAVB are secondary to the inability to increase heart rate, and hence cardiac output, in response to varying physiologic demands. For symptomati...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • between 10 and 21 years of age
- • structurally normal heart
- • congenital complete heart block
- • dual chamber pacemaker, right ventricular apex paced
- • normal function via traditional transthoracic echocardiography
- Exclusion Criteria:
- • preexisting condition that precludes patient from exercise
- • no informed consent
About Emory University
Emory University, a leading research institution located in Atlanta, Georgia, is dedicated to advancing medical knowledge and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, Emory harnesses the expertise of its renowned faculty and state-of-the-art facilities to conduct cutting-edge research across various fields, including oncology, neurology, and infectious diseases. The university's commitment to ethical research practices and patient safety ensures that all clinical trials are designed to generate valuable data that can lead to significant therapeutic advancements. By fostering partnerships with local hospitals and community organizations, Emory strives to translate research findings into real-world applications, ultimately enhancing health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Atlanta, Georgia, United States
Patients applied
Trial Officials
Patricio A Frias, MD
Principal Investigator
Emory University and Children's Healthcare of Atlanta
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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