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Search / Trial NCT00447486

A Study of GW842166 in Adults With Osteoarthritis Pain

Launched by GLAXOSMITHKLINE · Mar 12, 2007

Trial Information

Current as of May 29, 2025

Completed

Keywords

Osteoarthritis, Knee, Gw842166, Pain, Efficacy, Safety

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • male or female outpatient, \>= 40 years of age
  • meets ACR clinical and radiographic criteria for classification of idiopathic (primary) osteoarthritis of the knee with symptom duration for at least 3 months
  • meets ARA functional status requirements
  • meets WOMAC pain subscale score requirements
  • has taken analgesics for the treatment of their knee OA for at least 4 out of 7 days in each of the 4 weeks preceding screen
  • Exclusion Criteria:
  • any pre-specified clinical/biological/ECG abnormality
  • any pre-specified drug sensitivity
  • history of peptic ulceration or GI bleeding
  • use of protocol-specified medications
  • secondary cause of knee OA
  • lower extremity surgery within 6 months of screening
  • use of analgesics other than allowed per protocol
  • use of corticosteroids or hyaluronan outside of allowed window prior to screening

About Glaxosmithkline

GlaxoSmithKline (GSK) is a global healthcare company dedicated to improving the quality of human life by enabling people to do more, feel better, and live longer. With a strong focus on research and development, GSK specializes in pharmaceuticals, vaccines, and consumer health products. The company is committed to advancing innovative therapies and preventive measures across various therapeutic areas, including respiratory, oncology, immunology, and infectious diseases. GSK's collaborative approach and rigorous clinical trial processes underscore its dedication to delivering safe and effective healthcare solutions that meet the needs of patients worldwide.

Locations

Göteborg, , Sweden

Koeln, Nordrhein Westfalen, Germany

Madrid, , Spain

La Coruña, , Spain

Santiago De Compostela, , Spain

Hamburg, , Germany

Schmiedeberg, Sachsen, Germany

Odense C, , Denmark

Muenchen, Bayern, Germany

Essen, Nordrhein Westfalen, Germany

Helsingborg, , Sweden

Berlin, , Germany

Hvidovre, , Denmark

Leipzg, Sachsen, Germany

Centelles, , Spain

Petrer/Alicante, , Spain

Höllviken, , Sweden

Stocholm, , Sweden

Upplands Väsby, , Sweden

Patients applied

0 patients applied

Trial Officials

GSK Clinical Trials, BSc MB PhD

Study Director

GlaxoSmithKline

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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