The Anti-allergic Effects of Specific Probiotics

Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · May 25, 2007

Keywords

ClinConnect Summary

Probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit on the host". Many studies have been performed which indicate that probiotics can temporarily modify the composition of gut microbiota, and potentially these can reduce susceptibility to allergy (Noverr \& Huffnagle, 2005) (Tannock et al. 2000), leading to health benefits for the host. Numerous studies show that these benefits include ones primed through the immune response of the host.

Animals maintained free of microorganisms have drastic abnormalities in their immune response. These g...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinical diagnosis of allergic rhinitis based on sneeze attacks, runny/blocked/itchy nose in the absence of a common cold during the previous 12 months.
• • History of positive skin prick test or blood radio-allergosorbent test (RAST) to grass and/or ragweed pollen
• Exclusion Criteria:
• • Ongoing allergen immunotherapy
• • upper respiratory tract infection
• • Pregnancy
• • Clinical history of lactose-intolerance or allergies to cow-milk