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Search / Trial NCT00484939

A Study of Bevacizumab (Avastin) in Combination With Capecitabine (Xeloda) in Elderly Patients With Metastatic Colorectal Cancer

Launched by HOFFMANN-LA ROCHE · Jun 11, 2007

Trial Information

Current as of May 15, 2025

Completed

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult patients, ≥ 70 years of age.
  • Cancer of the colon or rectum.
  • Metastatic disease diagnosed ≤ 6 months before enrollment.
  • ≥ 1 measurable metastatic lesion.
  • Exclusion Criteria:
  • Adjuvant anti-vascular endothelial growth factor (VEGF) treatment.
  • Prior chemotherapeutic treatment for metastatic colorectal cancer.
  • Past or current history of other malignancies (with the exception of basal and squamous cell cancer of the skin, or in situ cancer of the cervix).
  • Clinically significant cardiovascular disease.
  • Current or recent daily use of aspirin (\> 325 mg/day) or other non-steroidal anti-inflammatory drug (NSAID), or full dose anticoagulants.

About Hoffmann La Roche

Hoffmann-La Roche, commonly known as Roche, is a global leader in biotechnology and pharmaceuticals, committed to advancing healthcare through innovative research and development. With a strong focus on oncology, immunology, infectious diseases, and central nervous system disorders, Roche leverages cutting-edge science to deliver transformative therapies and diagnostics. The company is dedicated to improving patient outcomes by conducting rigorous clinical trials and collaborating with healthcare professionals and organizations worldwide. Roche's unwavering commitment to precision medicine and personalized healthcare positions it at the forefront of the industry, driving progress in the quest for effective treatments and improved patient care.

Locations

Ottawa, Ontario, Canada

Roma, , Italy

Jaen, , Spain

Glasgow, , United Kingdom

Leicester, , United Kingdom

Manchester, , United Kingdom

Montreal, Quebec, Canada

Mexico City, , Mexico

Calgary, Alberta, Canada

Barcelona, , Spain

Madrid, , Spain

London, , United Kingdom

Budapest, , Hungary

Innsbruck, , Austria

Wien, , Austria

Linz, , Austria

Vancouver, British Columbia, Canada

Halifax, Nova Scotia, Canada

London, Ontario, Canada

Zaragoza, , Spain

Leon, , Mexico

Toronto, Ontario, Canada

Sutton, , United Kingdom

Seoul, , Korea, Republic Of

Ljubljana, , Slovenia

Larissa, , Greece

Nottingham, , United Kingdom

Utrecht, , Netherlands

Firenze, , Italy

Warszawa, , Poland

Gyor, , Hungary

Incheon, , Korea, Republic Of

Eindhoven, , Netherlands

Salzburg, , Austria

Murcia, , Spain

Puebla, , Mexico

Apeldoorn, , Netherlands

Rhyl, , United Kingdom

Reggio Emilia, Emilia Romagna, Italy

Krakow, , Poland

Colchester, , United Kingdom

Piraeus, , Greece

Zalaegerszeg Pozva, , Hungary

Lecce, Puglia, Italy

Gyeonggi Do, , Korea, Republic Of

Las Palmas De Gran Canaria, Las Palmas, Spain

Leganes, Madrid, Spain

Bristol, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Clinical Trials

Study Director

Hoffmann-La Roche

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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