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Search / Trial NCT00525772

Effect of Ciclesonide on Exercise Induced Bronchoconstriction

Launched by HAMILTON HEALTH SCIENCES CORPORATION · Sep 5, 2007

Trial Information

Current as of May 29, 2025

Completed

Keywords

Asthma Exercise Induced Bronchoconstriction Sputum Eosinophils

ClinConnect Summary

To study the effects of 4 doses of ciclesonide on exercise-induced bronchoconstriction, bronchial responsiveness to mannitol, sputum parameters and other parameters of asthma control in asthmatic patients. The primary aim was to evaluate exercise-induced bronchoconstriction as a method of determining the dose and time responses of inhaled corticosteroid therapy. The secondary aims were to evaluate the dose and time responses of sputum parameters and responsiveness to mannitol to inhaled corticosteroid therapy. Furthermore to explore the relationship(s) between exercise induced bronchoconstr...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • stable asthma not on maintenance asthma medications
  • exercise induced bronchoconstriction on dry air exercise challenge.
  • Exclusion Criteria:
  • other significant co-morbidity or treatments that might interfere with the conduct or results of the study
  • fail to return to baseline after a maximum washout period of 8 weeks
  • unable to perform the procedures of the study

About Hamilton Health Sciences Corporation

Hamilton Health Sciences Corporation is a leading healthcare provider in Canada, renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a focus on translating scientific discoveries into effective treatments, the organization operates a network of hospitals and specialized centers that facilitate cutting-edge research across various medical disciplines. Hamilton Health Sciences is dedicated to fostering collaboration among researchers, healthcare professionals, and industry partners, ensuring that clinical trials are conducted with the highest ethical standards and rigor. Through its robust research infrastructure, the corporation aims to enhance health outcomes and contribute to the global body of medical knowledge.

Locations

Hamilton, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Paul O'Byrne, MD

Principal Investigator

McMaster University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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