Efficacy and Safety of Etoricoxib in Acute Ankle Sprain: A Double-Blind Comparative Study Among 2 Treatments Protocols
Launched by NÚCLEO DE ESTUDOS EM ESPORTES E ORTOPEDIA, BRAZIL · Sep 4, 2007
Trial Information
Current as of May 12, 2025
Unknown status
Keywords
ClinConnect Summary
Study Objectives Primary
* To compare the efficacy of those 2 treatment doses in patients with acute ankle sprain in sports Secondary
* To compare the overall safety and tolerability of etoricoxib 60 mg and 90mg in patients with acute ankle sprain in sports
Hypothesis
* The efficacy of etoricoxib 60 mg once daily will be non-inferior to etoricoxib 90mg daily for 14 days in the treatment of acute ankle sprain in sports.
* The 60 mg dose of etoricoxib will have similarity in reducing the pain and will be more effective in decreasing the degree of edema, with most patients experiencing remi...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients that suffered an ankle sprain in the last 12 hours and seek medical assistance
- Exclusion Criteria:
- • anterior history of trauma / fractures in the affected ankle
- • history of hypertension / gastrointestinal problems
- • patients that did not agree to sign the informed consent to participate in the study
About Núcleo De Estudos Em Esportes E Ortopedia, Brazil
Núcleo de Estudos em Esportes e Ortopedia (NESO) is a leading clinical research organization based in Brazil, dedicated to advancing the fields of sports medicine and orthopedics. With a commitment to high-quality research and innovation, NESO collaborates with healthcare professionals, academic institutions, and industry partners to conduct rigorous clinical trials that aim to enhance treatment outcomes and improve the quality of life for patients. The organization focuses on integrating scientific evidence with practical applications in sports and orthopedic care, fostering a multidisciplinary approach to address the complex needs of athletes and individuals with musculoskeletal conditions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
São Paulo, Sp, Brazil
Patients applied
Trial Officials
Rogerio T Silva, MD, PhD
Principal Investigator
NEO - Orthopedic Sports Medicine Research Center
Lidia F Souza, PT
Study Director
NEO - Orthopedic Sports Medicine Research Center
Cristiano FS Laurino, MD
Study Director
NEO - Orthopedic Sports Medicine Research Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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