Digital Colposcopy in Finding Cervical Intraepithelial Neoplasia

Launched by BRITISH COLUMBIA CANCER AGENCY · Jan 25, 2008

Keywords

ClinConnect Summary

OBJECTIVES:

* To identify potential improvements for a noninvasive method of diagnosing cervical dysplasia and neoplasia using digital colposcopy and fluorescence spectroscopic imaging.
* To measure fluorescence and reflectance images of the human cervix in vivo using digital colposcopy.
* To evaluate the effect of acetic acid on the image contrast obtained.
* To compare the device performance with colposcopic impression and histopathologic interpretation of tissue removed by standard loop electrosurgical excision procedure (LEEP).

OUTLINE: This is a multicenter study.

Participants under...

Gender

FEMALE

Eligibility criteria

• Criteria:
• Inclusion criteria:
• • Included subjects will be ≥18 years old.
• • Included subjects will not be pregnant.
• • Included subjects will have a negative urine pregnancy test.
• • Included subjects will be scheduled for colposcopy and/or LEEP treatment at the VGH Women's Clinic.
• • Included subjects will indicate understanding of the study.
• • Included subjects will provide informed consent to participate.
• Exclusion criteria:
• • Individuals \<18 years old will be excluded.
• • Pregnant individuals will be excluded.
• • Individuals that have had an operation to remove their cervix will be excluded.
• PRIOR CONCURRENT THERAPY:
• • See Disease Characteristics