Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Jun 10, 2008

Keywords

ClinConnect Summary

Participation in this study will last approximately 12 months and will involve individuals with recent-onset schizophrenia. All participants will undergo baseline assessments that will include an interview, written tests, blood draws, and electroencephalogram (EEG) and magnetic resonance imaging (MRI) scans. Participants will then be assigned randomly to receive treatment with either computerized neuroadaptive cognitive training or commercially available computer games. Participants will be asked to complete 60-minute sessions of their assigned treatments 5 days per week for 8 weeks. For pa...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinical diagnosis of schizophrenia, schizophreniform, or schizoaffective disorder
• • First psychotic episode within the last 3 years
• • Good general physical health
• • Age between 12-35
• • Is fluent and proficient in the English language
• • Achieved clinical stability (e.g., outpatient status for at least 3 months before study entry; on stable doses of medication for at least 1 month before study entry
• • Minors must have parental/legal guardian consent to participate
• Exclusion Criteria:
• • Any neurological disorder
• • History of psychoactive substance abuse in the past 6 months

Trial Officials