Cardiac Resynchronization Therapy (CRT)-Narrow-dp/Dt-Study

Launched by MEDTRONIC BAKKEN RESEARCH CENTER · Jan 13, 2009

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • EF \< 35%
• • CHD or dilate cardiomyopathy
• • sinus rhythm
• • NYHA III (or IV but stable recompenstated)
• * QRS \< 120 ms 2-3 of the following:
• • LV-fillingtime \< 40% of the cyclelength
• • TDI septal-lateral (LV basal) \> 60ms
• • 2D-Strain-Score \> 9 points
• Exclusion Criteria:
• • tricuspid or artificial valve
• • AV block II or III or PQ time \> 250ms
• • revasculisation or condition after cardiac surgery \< 3 months
• • myocardial infarction or bypass OP \< 3 months
• • hytertrphic obstructive cardiomyopathy, constrictive pericarditis
• • intravenous catecholamines because of HF
• • manifeste hyperthyreoses
• • kidney failure (creatine \>2,5 mg/dl)
• • no written informed consent
• • no compliance
• • participation in another study
• • life expectancy \< 1 year
• • patients \< 18 years
• • pragnancy or no safe contraception