Fatigue and Pancreas and Bile Duct Cancer Study

Launched by SIDNEY KIMMEL CANCER CENTER AT THOMAS JEFFERSON UNIVERSITY · May 14, 2009

Keywords

ClinConnect Summary

Pancreatic cancer (PC) is the fourth leading cause of cancer death in men and fifth in women in the US (Jemal, Sigel, Ward, Murray, Xu, Thun et al., 2007). According to the American Cancer Society, the reported incidence of PC is roughly 37,000 cases per year, with approximately 33,000 annual deaths (2007). Periampullary cancers are less common; there were 9,250 incident cancers of the biliary tract in 2007, with 3,250 resultant deaths (Jemal et al., 2007).

Five-year survival rates for untreated PC and periampullary cancers are poor, approximately 4%. Surgery offers the only hope of a cure...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Confirmed pathologic diagnosis of adenocarcinoma of pancreas or periampullary cancers, Stage I, II, or III
• • Treatment included surgery alone, or adjuvant treatment with CT and/or RT
• • Men and women ≥ 18 years of age
• • Residents of the USA
• • Surgery performed at TJUH, Philadelphia, PA
• • CT or RT performed at TJUH, Jefferson system affiliate hospital, or elsewhere
• • Patients receiving neoadjuvant therapy with CT or RT, or both, who subsequently are re-staged and eligible for surgery
• Exclusion Criteria:
• • The presence of co-morbidities that would preclude involvement in a walking program (wheelchair bound, severe arthritis, dizziness)
• • Primary residence outside the USA
• • Medical management alone for pancreas or periampullary cancer (i.e. not a surgical candidate)
• • Stage IV (metastatic) cancer