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Search / Trial NCT00940654

The Fever and Antipyretic in Critically Illness Evaluation Study

Launched by JAPANESE SOCIETY OF INTENSIVE CARE MEDICINE · Jul 15, 2009

Trial Information

Current as of May 30, 2025

Completed

Keywords

Fever Antipyretic Infection Mortality Cooling Non Steroid Anti Inflammatory Drugs Acetaminophen Steroid Icu Intensive Care Critically Ill

ClinConnect Summary

Fever is common in critically ill patients.Antipyretic therapy for fever is routinely performed in intensive care.There are studies to assess the relationship between fever and mortality in non-neurological ICU. However, all of them did not have any information of antipyretic therapy. There are two small, single center RCT, which suggested a potential risk for antipyretic therapy. Thus, a large RCT might be ethically difficult.

It is unfortunate that there is not enough information on how the investigators should control body temperature in non-neurological critically ill patients, because...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult non-neurological critically ill patients (20 years old or older).
  • ICU patients expected to require intensive care for more than 48 hour.
  • Exclusion Criteria:
  • Patients with brain injury (suspected or proven)

About Japanese Society Of Intensive Care Medicine

The Japanese Society of Intensive Care Medicine (JSICM) is a leading professional organization dedicated to advancing the field of intensive care medicine in Japan. With a mission to promote high standards of care, education, and research, JSICM supports clinical trials that aim to improve patient outcomes and enhance the efficacy of critical care practices. The society fosters collaboration among healthcare professionals, researchers, and institutions, facilitating the dissemination of knowledge and innovative approaches in intensive care. Through its commitment to evidence-based medicine and multidisciplinary cooperation, JSICM plays a pivotal role in shaping the future of critical care in Japan and beyond.

Locations

Bunkyo Ku, Tokyo, Japan

Songpa Gu, Seoul, Korea, Republic Of

Patients applied

0 patients applied

Trial Officials

Younsuck Koh, M.D. PhD

Study Chair

Korean Society of Critical Care Medicine

Masaji Nishimura, M.D. PhD

Study Chair

Japanese Society of Intensive Care Medicine

Jae Yeol Kim, M.D.

Principal Investigator

Korean Society of Critical Care Medicine

Gee Young Suh, M.D.

Principal Investigator

Korean Society of Critical Care Medicine

Moritoki Egi, M.D.

Principal Investigator

Japanese Society of Intensive Care Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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