Gastric Functions & Proton Pump Inhibitor( PPI) Study
Launched by CHINESE UNIVERSITY OF HONG KONG · Aug 3, 2009
Trial Information
Current as of June 10, 2025
Completed
Keywords
ClinConnect Summary
Background
Functional dyspepsia is one of the commonest digestive disorders. It is a functional gastrointestinal disorder which is characterized by chronic recurrent epigastric symptoms such as pain, burning and a variety of postprandial symptoms with absence of demonstrable organic pathology identified on investigations. It has been reported that functional dyspepsia affects 10-30% of adult population.
The pathophysiology of functional dyspepsia is uncertain. It is thought to be a heterogeneous disorder. Various factors have been implicated in the pathophysiology of functional dyspepsia....
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with functional dyspepsia that fulfill Rome III criteria attending GI clinic or endoscopy center
- • Age 18-60 years old
- • Provision of written consent
- • Negative upper endoscopy (oesophagogastroduodenoscopy or OGD) finding
- Exclusion Criteria:
- • Diabetes mellitis
- • Frequent (once or more per week) acid reflux or heartburn symptoms
- • Concurrent medications that affect GI motility
- • Concurrent use of TCA
- • History of gastric surgery
- • Organic disease as cause of dyspepsia
- • H. pylori infection
- • Use of PPI or NSAID in the past 4 weeks
- • Pregnancy
- • Known hypersensitivity to PPI
About Chinese University Of Hong Kong
The Chinese University of Hong Kong (CUHK) is a prestigious research institution renowned for its commitment to advancing medical science and improving healthcare outcomes. As a clinical trial sponsor, CUHK leverages its extensive academic resources and interdisciplinary expertise to conduct innovative research that addresses critical health challenges. The university fosters collaboration among leading researchers, healthcare professionals, and industry partners, ensuring rigorous study design and implementation. CUHK is dedicated to upholding the highest ethical standards in clinical research, with a focus on translating findings into tangible benefits for patients and the broader community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hong Kong, , Hong Kong
Patients applied
Trial Officials
Justin C.Y. Wu, MBChB(CUHK)
Principal Investigator
Chinese University of Hong Kong
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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