ClinConnect ClinConnect Logo
Search / Trial NCT00978016

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Launched by XENOPORT, INC. · Sep 15, 2009

Trial Information

Current as of June 14, 2025

Completed

Keywords

Gerd

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. confirmed diagnosis of GERD by a gastroenterologist
  • 2. minimum of 3 months of GERD symptoms prior to screening.
  • 3. currently taking an FDA approved dose of PPI therapy for symptomatic GERD for at least 4 weeks prior to screening
  • 4. experienced partial relief of GERD symptoms while receiving approved dose and regimen of PPI therapy
  • 5. experienced GERD symptoms, defined as heartburn (with or without regurgitation or other GERD symptoms) on ≥ 3 days during the week prior to screening
  • Exclusion Criteria:
  • 1. evidence of erosive esophagitis or erosive gastritis on upper gastrointestinal endoscopy during screening
  • 2. has not experienced any GERD symptom improvement after an adequate course of PPI treatment (at least 2 weeks)
  • 3. unstable or severe medical condition

About Xenoport, Inc.

XenoPort, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of neurological and autoimmune disorders. Leveraging its proprietary drug delivery technology, XenoPort aims to enhance the bioavailability and effectiveness of existing medications while minimizing side effects. The company is committed to advancing its pipeline of novel compounds through rigorous clinical trials, with a strong emphasis on scientific excellence and patient-centric approaches. XenoPort collaborates with healthcare professionals and research institutions to bring transformative solutions to patients in need.

Locations

Metairie, Louisiana, United States

Columbus, Ohio, United States

Ann Arbor, Michigan, United States

Scottsdale, Arizona, United States

San Diego, California, United States

Stanford, California, United States

Atlanta, Georgia, United States

Waterbury, Connecticut, United States

Huntsville, Alabama, United States

Charlotte, North Carolina, United States

Colorado Springs, Colorado, United States

Great Neck, New York, United States

Littleton, Colorado, United States

Binghamton, New York, United States

Fayetteville, North Carolina, United States

Germantown, Tennessee, United States

Tucson, Arizona, United States

Shreveport, Louisiana, United States

Annapolis, Maryland, United States

Lakewood, Colorado, United States

Lexington, Kentucky, United States

Brockton, Massachusetts, United States

Ogden, Utah, United States

Salt Lake City, Utah, United States

Clive, Iowa, United States

Raleigh, North Carolina, United States

Anaheim, California, United States

Lake Success, New York, United States

Jupiter, Florida, United States

Baton Rouge, Louisiana, United States

Lancaster, California, United States

Fargo, North Dakota, United States

Lafayette, Colorado, United States

Mission Hills, California, United States

Pembroke Pines, Florida, United States

Toronto, Ontario, Canada

Greensboro, North Carolina, United States

Lake Jackson, Texas, United States

San Antonio, Texas, United States

Madisonville, Kentucky, United States

Christiansburg, Virginia, United States

Guelph, Ontario, Canada

Egg Harbor Township, New Jersey, United States

Pittsburgh, Pennsylvania, United States

Norman, Oklahoma, United States

Uniontown, Pennsylvania, United States

Bellaire, Texas, United States

Charlottesville, Virginia, United States

Chandler, Arizona, United States

Sacramento, California, United States

Westlake Village, California, United States

Milford, Connecticut, United States

Monroe, Louisiana, United States

Brooklyn, New York, United States

Mesa, Arizona, United States

Chattanooga, Tennessee, United States

Sherwood, Arkansas, United States

Hagerstown, Maryland, United States

Johnson City, New York, United States

Logan, Utah, United States

Waukesha, Wisconsin, United States

Patients applied

0 patients applied

Trial Officials

Study Director

Study Director

XenoPort, Inc.

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials