Effect of Rivaroxaban on Coagulation Parameters- an ex Vivo Study
Launched by JOHANN WOLFGANG GOETHE UNIVERSITY HOSPITAL · Sep 29, 2009
Trial Information
Current as of April 29, 2025
Completed
Keywords
ClinConnect Summary
To validate the effects of Rivaroxaban on coagulation parameters plasma samples of patients after hip or knee replacement surgery treated with Rivaroxaban 10 mg/d are investigated.
Plasma samples are obtained by blood collection before, after 2 hours and after 12 hours after Rivaroxaban dosing in steady state (on 3rd - 5th day).
Several techniques, including clot-based tests, chromogenic assays and ELISA´s are used for coagulation assays in our coagulation laboratory Frankfurt/Main. The influence of Rivaroxaban on different coagulation assays should be investigated in our coagulation labo...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients after hip or knee replacement surgery treated with Rivaroxaban 10 mg/d
- • must be able to accept blood sampling
About Johann Wolfgang Goethe University Hospital
Johann Wolfgang Goethe University Hospital, located in Frankfurt am Main, Germany, is a prominent academic medical center affiliated with Goethe University. Renowned for its commitment to advancing healthcare through innovative research and clinical excellence, the hospital serves as a vital hub for clinical trials and medical studies. It integrates cutting-edge technology with a multidisciplinary approach, facilitating collaboration among healthcare professionals to enhance patient outcomes. The hospital is dedicated to ethical research practices and adheres to stringent regulatory standards, ensuring the safety and well-being of trial participants while contributing to the advancement of medical science.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Frankfurt Am Main, , Germany
Patients applied
Trial Officials
Helen Mani, PhD
Principal Investigator
Johann Wolfgang Goethe University Hospital Frankfurt/Main Germany
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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