ClinConnect ClinConnect Logo
Search / Trial NCT00992381

Comparison Study of a New Combination of 2 Marketed Medications (Esomeprazole and Naprosyn) Versus Naprosyn Alone

Launched by ASTRAZENECA · Oct 8, 2009

Trial Information

Current as of April 28, 2025

Completed

Keywords

Gi Pain Healthy Participants Safety Bioavailability

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subjects must have a body weight greater than 50 kg and BMI within the range 18-30(inclusive).
  • Subjects must be in good health, as assessed during pre-study medical examination and by review of screening results
  • Subjects must understand the procedures involved and agree to participate in the study by giving fully informed, written consent
  • Exclusion Criteria:
  • Significant intercurrent disease of any type, in particular liver, kidney, cardiovascular disease, any form of diabetes or significant gastrointestinal disorder which could affect drug absorption, or any history of gastric or duodenal ulceration.
  • Ingestion of any naproxen, omeprazole, esomeprazole or related drugs prior to the recruitment interview, such that these drugs will have been ingested in the 4 weeks prior to the day set for the first Period 1 dose

About Astrazeneca

AstraZeneca is a global biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines across various therapeutic areas, including oncology, cardiovascular, respiratory, and autoimmune diseases. With a strong commitment to scientific research and patient-centric solutions, AstraZeneca leverages cutting-edge technology and a robust pipeline to address unmet medical needs. The company collaborates with healthcare professionals, academic institutions, and other organizations to advance clinical trials and deliver transformative therapies, aiming to improve health outcomes and enhance the quality of life for patients worldwide.

Locations

Brisbane, Queensland, Australia

Patients applied

0 patients applied

Trial Officials

Terry Hurst

Study Director

Q-Pharm Phase one unit

Jo Marjason

Principal Investigator

Q-Pharm Phase one unit

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials