Recto Anal Repair or Milligan Morgans Operation of Grade 3 and 4 Symptomatic Haemorrhoidal Disease
Launched by UNIVERSITY HOSPITAL, AKERSHUS · Dec 22, 2009
Trial Information
Current as of June 20, 2025
Terminated
Keywords
ClinConnect Summary
An estimated 4% of the adult population suffers from haemorrhoidal disease. In 1937 E. T. Milligan and C. N. Morgan described a method for operating piles that still is regarded "the gold standard" in the treatment of severe haemorrhoidal disease. This procedure is followed by a prolonged and painful recovery. To overcome the long recovery often combined with long sick leaves, less invasive methods for treating piles have been introduced during the last decade. However, few studies have compared patient benefits and the long term outcome of these techniques, and the choice of treatment is o...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with symptomatic grade 3 and 4 haemorrhoidal disease
- • Age 18-80
- • Patients who are fitted for local and general anaesthesia
- • Patients who are able to understand the information given and are willing to give a written consent
- Exclusion Criteria:
- • Previous operated for piles
- • Previous operated in the anal canal
- • Faecal incontinence
- • Inflammatory bowel disease with affection of the anal canal
- • Chronic diarrhea
- • Fissura ani
- • Fistula in ano
- • Chronic anal pain
- • Neurological illness with affection of anal sensation
- • Patients not able to follow the study protocol
- • Patients taking immunosuppressant medication
- • Pregnancy
- • Disability
- • Anal polyps
- • Medication affecting the coagulation system
- • Circular anal prolapse
About University Hospital, Akershus
University Hospital Akershus is a leading clinical research institution dedicated to advancing medical knowledge and improving patient care through innovative trials. As a part of the University of Oslo, the hospital integrates cutting-edge research with clinical practice, fostering collaboration among multidisciplinary teams of healthcare professionals and researchers. With a strong emphasis on ethical standards and patient safety, University Hospital Akershus is committed to conducting high-quality clinical trials that address critical health challenges and contribute to the development of new therapies and treatments.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Lorenskog, , Norway
Patients applied
Trial Officials
Geir A Larsen, M.D., Ph.D.
Principal Investigator
University Hospital, Akershus
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials