A Prospective Randomized Study for Comparison of Y-Composite Grafts
Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Jan 17, 2010
Trial Information
Current as of June 15, 2025
Completed
Keywords
ClinConnect Summary
The SAVERITA trial was designed as a randomized, controlled trial to recruit 224 patients who undergo off-pump coronary artery bypass using Y-composite graft based on the left internal thoracic artery. Patients were randomized by use of a randomization table. Composite conduit was made using saphenous vein or right internal thoracic artery according to the randomization result. The primary end point is to evaluate early and 1-year postoperative graft patency. The secondary end points are overall survival, freedom from cardiac death and freedom from MACCE(major adverse cardiac or cerebrovasc...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • age equal or more than 40
- • age equal or less than 75
- • patients who agree to the enrollment
- Exclusion Criteria:
- • Patients with heart failure (left ventricular ejection fraction \< 25%)
- • patients who have intractable ventricular arrhythmia
- • patients who has been treated for cancer
- • patients who has infectious disease
- • patients who are planned to undergo combined cardiac surgery
- • patients who has medical co-morbidity with expected survival less than 1 year
- • patients who has a problem using right internal thoracic artery or saphenous vein
- • patients with a history of previous cardiac surgery
- • Patients with chronic renal failure
- • patients who undergo emergency operation
About Seoul National University Hospital
Seoul National University Hospital (SNUH) is a leading medical institution in South Korea, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, SNUH integrates cutting-edge scientific inquiry with patient-centered care, facilitating the development of novel therapies and treatment protocols. The hospital boasts a diverse range of specialized departments and a robust infrastructure for conducting clinical studies, ensuring rigorous adherence to ethical standards and regulatory compliance. By fostering collaboration among multidisciplinary teams, SNUH aims to contribute significantly to global medical advancements and improve patient outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Seoul, , Korea, Republic Of
Patients applied
Trial Officials
Ki-Bong Kim, MD, PhD
Principal Investigator
Department of throacic and cardiovascular surgery, Seoul National University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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