A Randomised Controlled Trial on the Effect of Post-exposure Oseltamivir Prophylaxis on Influenza Transmission in Nursing Homes
Launched by NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT (RIVM) · Jan 20, 2010
Trial Information
Current as of May 22, 2025
Unknown status
Keywords
ClinConnect Summary
Objective If proven (cost)effective, without inducing antiviral resistance, oseltamivir could have considerable benefits in this setting, although constraints relating to implementation need to be addressed as well. If not (cost)effective if this fragile population, resources can be better spent on other activities to support nursing home residents.
Study design:
A randomised controlled trial on the effect of PEP with oseltamivir versus placebo on transmission of influenza in nursing homes, linked to virological monitoring of possible development of resistance and impact on transmission a...
Gender
ALL
Eligibility criteria
- Exclusion Criteria:
- • Kidney dialyses
About National Institute For Public Health And The Environment (Rivm)
The National Institute for Public Health and the Environment (RIVM) is a prominent Dutch governmental research institute dedicated to enhancing public health and safeguarding the environment. Operating under the Ministry of Health, Welfare, and Sport, RIVM conducts comprehensive research and provides expertise in areas such as infectious disease control, environmental health, and health policy. Through its rigorous scientific studies and clinical trials, RIVM plays a critical role in informing public health strategies and interventions, ensuring evidence-based decision-making to improve population health outcomes and environmental sustainability.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bilthoven, Utrecht, Netherlands
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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